BACKGROUND Men who have sex with men (MSMs) are a vulnerable population for spread of Sexually Transmitted Diseases (STDs) and Human Immunodeficiency Virus (HIV). Apart from being important for HIV transmission, they tend to have different distribution patterns of STDs. Few Indian studies have looked into this aspect. Objective-We retrospectively analysed the available data on MSM from a tertiary care hospital from Jan 2015 to June 2016. MATERIALS AND METHODS We retrospectively analysed the available data on MSM visiting STD op, KGH, Vizag. The pattern of STDs was evaluated in each patient. RESULTS Syphilis was the most common STD followed by urethral discharge and herpes genitalis. CONCLUSION Identification of MSMs is important as most of them are bisexual and promiscuous, thereby playing a role in spread of STDs in vast number of partners. The profile of STDs also differs in MSM, which makes it all the more important to identify them.

Background: Acne vulgaris remains one of the commonest diseases of skin with chronic inflammatory dermatosis that affects 85 p.c of the adolescents and young adults globally. Acne is associated with greater psychological burden that include depression, anxiety, and low self-esteem. It is a multifactorial disease depending on genetic predisposition, follicular epidermal hyperproliferation, endocrine factors, the colonization and activity of Propionibacterium acnes, excess sebum production, inflammation, and environmental factors. Insulin resistance, dyslipidaemia, visceral adiposity, elevated blood pressure and chronic stress are several factors which constitute the metabolic syndrome.Aim & Objectives: To analyse the relationship between Diabetes Mellitus, Dyslipidaemia, Hypertension, and Visceral Adiposity in Acne Vulgaris. Material and Methods: A hospital based, analytical cross-sectional study was conducted among patients aged 14 years & above, irrespective of gender with acne vulgaris, irrespective of severity and attend the outpatient clinic of dermatology at a tertiary care hospital for a period of 12 months. Grading of acne was done according to Global Acne Grading System. Metabolic syndrome was diagnosed as per the criteria of the modified NCEP-ATP III. Results:The patients with severe GAGS had high metabolic syndrome (72.4%) when compared to those without metabolic syndrome (27.6%), there exists an extreme statistically significant association between metabolic syndrome and GAGS (acne severity) with p-value <0.001. Conclusion: HDL has high influence on acne vulgaris when compared to waist circumference, triglyceride, fasting blood sugar, and blood pressure.

<p class="abstract"><strong>Background: </strong>Among all the nutritional causes of hair loss, iron levels are found to be important key nutrient. Synthesis of hair involves many steps which require iron as a cofactor. The intention of present study is to evaluate relationship between iron and hair loss. The objectives of the study are to study the clinical patterns, demographic and epidemiological factors associated with hair loss and to find association between iron study parameter (Hb, serum iron, serum ferritin, TIBC) and hair loss.</p><p class="abstract"><strong>Methods: </strong>The study was a cross section- observational study, conducted among the patients with diagnosed non-cicatricial alopecias from June 2018 to April 2019. A total of 50 study participants were recruited. Specific investigations like hair pull test and trichogram were done. Chi square test was applied and p&lt;0.05 was considered significant.</p><p class="abstract"><strong>Results:</strong> Among the total 50 participants 35 (70%) were males and 15 (30%) were females. Mean (±SD) age was 44 (±9.5) years. Mean (SD) of haemoglobin, serum iron, TIBC and ferritin are 9.6 (±2.6), 75.5 (±50), 365 (±54) and 106 (±87) respectively. Trichogram result proves telogen hair- 22 (44%), dystrophic hair loss- 14 (28%) and anagen hair loss-14 (28%). Hair pull test was positive in 27 (54%). Higher proportion of male pattern hair loss was associated with lower haemoglobin and low serum ferritin levels. (p value -0.046, 0.031)</p><p class="abstract"><strong>Conclusions:</strong> Significant association was found between the diagnosis of non cicatricial alopecia and mean values of haemoglobin and serum ferritin with lower haemoglobin and low serum ferritin was mostly associated with male pattern hair loss.</p>

<p class="abstract"><strong>Background:</strong> Psoriasis is a disease of systemic inflammation with multiple organ ramifications. It is a chronic, painful, non-communicable, immune-mediated, genetic disease-causing disfiguration and disability, for which there is no cure and with great negative impact on patients’ quality of life (QoL). Aim and objective was to assess the efficacy and safety of adalimumab (ADA) in moderate to severe plaque psoriasis.</p><p class="abstract"><strong>Methods:</strong> A hospital based, analytical retrospective observational study was conducted among patients aged 18 years and above, irrespective of gender and who received adalimumab treatment for moderate-to-severe plaque psoriasis and attended the outpatient clinic of dermatology at a tertiary care hospital for a period of 12 months. Efficacy was evaluated in all patients at 4, 12 and at last visit by calculating PASI (psoriasis area and severity index) relative to pre-treatment visit (baseline 0 week) as there was no comparative group. Safety was assessed by recording of side effects if any. Data was entered in MS excel 2019 and statistical analysis was done using SPSS 23 demo version.<strong></strong></p><p class="abstract"><strong>Results:</strong> The mean PASI score at 0 week was 24.4±3.26, this when compared to PASI score at 4 weeks (11.2±4.08), at 12 weeks (3.2±2.40), at 52 weeks (0.5±0.96) had shown an extreme statistically significant difference. Side effects reported were urticaria, diarrhea, upper respiratory tract infections.</p><p class="abstract"><strong>Conclusions:</strong> Adalimumab was very effective for chronic psoriasis, when given at high loading dose followed by maintenance dose every other week with minimal side effects.</p><p class="abstract"> </p><p align="left"> </p>

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