Purpose of reviewCannabis use is becoming more frequent in patients with inflammatory bowel disease (IBD). Because of the increased usage, gastroenterologists need to be cognizant of the benefits and risks associated with cannabis use in the IBD-patient population.Recent findingsRecent studies have attempted to determine whether cannabis can improve biomarkers or endoscopic findings of inflammation in patients with IBD, but the results have been inconclusive. However, cannabis has been shown to have an impact on the symptoms and quality of life of individuals with IBD. Despite these benefits, the use of cannabis in IBD is not without risks, including the potential for systemic illness, toxin ingestion and significant drug interactions.SummaryIn this review article, we use a case-based approach to discuss the critical clinical data that informs us of the benefits and risks of cannabis use in IBD. The endocannabinoid system plays a crucial role in regulating various physiological functions including the gastrointestinal tract. Studies have investigated the impact of cannabis on various medical conditions, including IBD. Clinicians must be aware of the most recent data to properly educate their patients on the benefits and risks of its use.

Discussion: EUS with FNA is an underutilized but highly valuable diagnostic method for extrapulmonary Coccidiomycosis. To our knowledge, this is one of the first cases in which EUS was utilized to diagnose disseminated Coccidiomycosis with lymphadenopathy as an etiology of recurrent pancreatitis. In this case, biopsy of peri-pancreatic lymphadenopathy from coccidiodes was deemed the etiology of recurrent pancreatitis by compressing pancreaticobiliary system.[2860] Figure 1. Top: EUS revealed multiple lymph nodes in the periportal and peripancreatic area. Bottom: EUS-guided fine needle biopsy was performed on the largest lymph node measuring 2 cms.

Introduction: Helicobacter pylori (H. pylori) is a widely prevalent infection considered a significant public health challenge. It is a major cause of gastroduodenal disorders, including gastric cancer. Thus prompt diagnosis and treatment are required for eradication. Nigeria has the highest worldwide H. pylori prevalence. Aims: To determine the spectrum of endoscopic findings in patients with H.pylori infectionat a tertiary care academic medical center. Methods: This retrospective hospital-based study was conducted between April 2018 and April 2022 among patients aged $18 years with dyspepsia. H. pylori was evaluated using non-invasive tests (urea breath test and fecal antigen test). Patients who tested positive for H. pylori and were further assessed with upper gastrointestinal endoscopy were included in the study. Demographics, clinical data, and endoscopic findings were extracted for analysis. A descriptive analysis of data obtained was carried out using SPSS version 20. Results: One hundred and twenty-nine (129) patients tested positive for H. pylori infection out of the two hundred and eighty dyspeptic patients evaluated during the period under study. However, only fifty-two (52) out of 129 dyspepticpatients who tested positive for H.pylori were evaluated with upper gastrointestinal endoscopy and thus met the inclusion criteria. Thirty-one (59.62%) were males, and 21 (40.38%) were females. The mean age was 45.65 years, with a range of 21-76 years. (Figure ) Upper gastrointestinal endoscopy among the patients revealed predominantly gastritis 37 (71.15%), with gastritis involving the corpus and antral area being the most typical form. Others were gastro-duodenitis in 4 (7.7%), esophagitis in 4 (7.7%), gastric ulcer in 3 (5.8%), and duodenal ulcer in 2 (3.8%), and gastric tumor in 2 (3.8%). Conclusion: Our study revealed that gastritis was the predominant endoscopic finding in patients with H. pylori infection. This finding is particularly significant because of the risk of progression of chronic gastritis in some of these patients to intestinal metaplasia, dysplasia, and gastric cancer. Hence, endoscopy with gastric biopsy should be obtained in patients with gastric erythema for early diagnosis and treatment.[0641] Figure 1. Socio demographics and spectrum of the endoscopic images A-Sex distribution of the study population. B-Age distribution of the study population. C-Endoscopic findings of the study population. D-Endoscopic image showing a widespread patchy redness involving the corpus and the antrum. E-Endoscopic image of fungating gastric mass involving the body and the antrum. F-Endoscopic image of a Forrest III gastric ulcer located on the lesser curvature.

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