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The case history is presented of a man 22 years of age who develope(l cardiac tamponallde in association wAith anticoagulant therapy and nonp)enetrating trauma of the heart. Included is a commentar'y on the delayed appearance of signs indicative of pericardial and/or myocar(lial daniage following severe trauma and the value of serial electrocardiographic observations in the diagnosis thereof.The importance of interpretation of the results of prothrombin testing is discussed and comparative data are presented which indicate the desirability for standardization of methods employed in reporting prothrombin values when used to control anticoagulant therapy wsith dicuilnai'ol.

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