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For exclusion of genetic disease, day 5-6 blastocyst-stage biopsies are more likely to be followed by implantation and singleton births than is the case after PGD performed on day 3.

Advances in tissue preservation have led to the commercialization of human placental membranes for the purposes of wound management with each product being characterized by different compositions and properties. The a priori specification of the research question in this investigator‐initiated study focused on the clinical outcomes in two nonrandomized, however statistically equal and homogenous patient cohorts receiving either a viable intact cryopreserved human placental membrane (vCPM) or a dehydrated human amnion/chorion membrane (dHACM), for the management of wounds at a single center. A total of 79 patients with 101 wounds were analyzed: 40 patients with 46 wounds received vCPM and 39 patients with 55 wounds received dHACM. The proportion of wounds achieving complete wound closure was 63.0% (29/46) for vCPM and 18.2% (10/55) for dHACM (p < 0.0001) for all treated wounds combined. This is the first comparative effectiveness study to report on the clinical outcomes associated with the use of different placental wound care products once broadly implemented in the clinical setting.

The chromosomes of the Asian mice, Mus fulvidiventris (boodugal), are typical of the Mus in general, viz., 40 telocentric chromosomes. The centromeric heterochromatin does not fluoresce brightly. The G band pattern of the euchromatin is the same as that of M. musculus. The diploid number of M. dunni is also 40, but each autosome possesses a short, heterochromatic second arm. The X chromosome is a long submetacentric, whose entire short arm and the terminal segment of the long arm are heterochromatic. The Y is a long telocentric and is heterochromatic. The G band pattern of the long arms of M. dunni is again very similar to that of M. musculus. Thus, karyotypic changes in M. dunni involved only the addition of C bands. Mus dunni and M. booduga are sympatric in many localities in India, but they can be separated by karyological and subtle morphological differences.

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