The paper presents a novel approach, based on deep learning, for diagnosis of Parkinson's disease through medical imaging. The approach includes analysis and use of the knowledge extracted by Deep Convolutional and Recurrent Neural Networks (DNNs) when trained with medical images, such as Magnetic Resonance Images and DaTscans. Internal representations of the trained DNNs constitute the extracted knowledge which is used in a transfer learning and domain adaptation manner, so as to create a unified framework for prediction of Parkinson's across different medical environments. A large experimental study is presented illustrating the ability of the proposed approach to effectively predict Parkinson's, using different medical image sets from real environments.

The paper presents a novel deep learning approach, which extracts latent information from trained Deep Neural Networks (DNNs) and derives concise representations that are analyzed in an effective, transparent way for prediction in medical imaging. A novel methodology is presented, in which deep neural architectures that have been trained to provide highly accurate predictions over existing datasets are adapted, in a consistent way, to make predictions over different contexts and datasets. Unified prediction is then achieved over the original and the new datasets. Successful application is illustrated through a large experimental study for prediction of Parkinson's disease from MRI and DaTScans, as well as for prediction of COVID-19 from CT scans and X-rays.

A novel machine learning approach is presented in this paper, based on extracting latent information and using it to assist decision making on ambulance attendance and conveyance to a hospital. The approach includes two steps: in the first, a forward model analyzes the clinical and, possibly, non-clinical factors (explanatory variables), predicting whether positive decisions (response variables) should be given to the ambulance call, or not; in the second, a backward model analyzes the latent variables extracted from the forward model to infer the decision making procedure. The forward model is implemented through a machine, or deep learning technique, whilst the backward model is implemented through unsupervised learning. An experimental study is presented, which illustrates the obtained results, by investigating emergency ambulance calls to people in nursing and residential care homes, over a one-year period, using an anonymized data set provided by East Midlands Ambulance Service in United Kingdom.

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A methodology is proposed in this paper allowing the classification of anomalies and subsequently their possible localization in nuclear reactor cores during operation. The method relies on the monitoring of the neutron noise recorded by in-core neutron detectors located at very few discrete locations throughout the core. In order to unfold from the detectors readings the necessary information, a 3-dimensional Convolutional Neural Network is used, with the training and validation of the network based on simulated data. In the reported work, the approach was also tested on simulated data. The simulations were carried out in the frequency domain using the CORE SIM+ diffusion-based two-group core simulator. The different scenarios correspond to the following cases: a generic “absorber of variable strength”, axially travelling perturbations at the velocity of the coolant flow (due to e.g. fluctuations of the coolant temperature at the inlet of the core), fuel assembly vibrations, control rod vibrations, and core barrel vibrations. In all those cases, various frequencies were considered and, when relevant, different locations of the perturbations and different vibration modes were taken into account. The machine learning approach was able to correctly identify the different scenarios with a maximum error of 0.11%. Moreover, the error in localizing anomalies had a mean squared error of 0.3072 in mesh size, corresponding to less than 4 cm. The proposed methodology was also demonstrated to be insensitive to parasitic noise and will be tested on actual plant data in the near future.