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AND CONCLUSIONS Benzpyrinium (Stigmonene) bromide and the experi¬ mental cholinergic compound W341 are clinically eval¬ uated in a total of 160 patients with established postoperative urinary retention. In the absence of urinary tract disease the 2 mg. dose of benzpyrinium bromide as well as the 1 mg. dose of the cholinergic compound W341 has been found to considerably shorten the duration of vesical atonia, thus reducing markedly the necessity for catheterization and/or the number of individual catheterizations. Episodes of toxicity have not been encountered with the administration of either the 1 mg. or 2 mg. dose of benzpyrinium bromide or the 1 mg. dose of compound W341. Both compounds were found to be effective but gentle in action and safe for both old and young patients.