Background: Organic synthesis has contributed significantly to the development of new drugs. Cyclic imides are organic functions that demonstrate therapeutic potential, due to their easy attainment and good yields. The development of new drugs often requires the creation of a library of compounds for further biological tests. However, organic syntheses are known to be mostly delayed. The use of microwave radiation in organic synthesis has increased in the last years, several studies in the area showed advantages such as decrease or total absence of solvents, increase of yield and mainly reduction of reaction time. The reaction conditions used to obtain 3,4-dichloro-1phenyl-1 H -pyrrole-2,5-dione, on dielectric heating at reflux, from dichloromaleic anhydride and aniline, using acetic acid as a catalyst, ethanol as solvent , yielded good results, yielding from 39.56 to 70.21% and time from 15 to 20 minutes. The literature records yield for this synthesis of 70%, under heating and reflux for 2 hours. Therefore, the dielectric heating was more efficient when compared to traditional heating.
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