Objective: To determine the frequency of Right Ventricle infarction and in-hospital outcome after primary percutaneous coronary intervention in patients with acute inferior MI. Study Design: Descriptive Cross Sectional Study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Diseases, from Dec 2018 to Jun, 2019. Methodology: Non-probability consecutive sampling technique was used. Permission was sought from hospital ethical committee and informed consent was taken from participants of the study. Patients presenting with acute inferior MI who underwent Primary Percutaneous Coronary Intervention were assessed for presence of Right Ventricle infarct. All the patients’ data and variables of the study was recorded in the data collection sheet. Patients underwent venous blood sampling for Complete blood count, Renal function tests, Liver function tests, Blood glucose random, Troponin-I, cardiac enzymes and Coagulation profile at presentation in emergency department. Results: Total 261 patients were included according to the inclusion criteria of the study. Mean age (years) in the study was 58.0 ± 12.59 whereas there were 183 (70.1) male and 78 (29.9) female patients who were included in the study. Frequency of right ventricular infarction and in-hospital outcome (mortality) after Primary Percutaneous Coronary Intervention in patients with acute inferior MI was assessed in the study which was 73 (28.0) and 20 (7.7) respectively. Conclusion: The study concluded that frequency of in-hospital mortality is substantial due to major adverse cardiac events in patients with right ventricle infarction.

Objective: To study the short-term and long-term outcomes of left main angioplasty at AFIC-NIHD. Study Design: Descriptive cross-sectional study. Place and Duration of Study: Armed Forces Institute of Cardiology/National Institute of Heart Disease (AFIC/NIHD) in 2018. Methodology: All cases of left main angioplasty done in 2018 were included in the study. The patients were followed up in clinic or on telephone and mortality (in-hospital, 30 days) outcomes and survival duration were recorded. Kaplan Meier curves were generated to show the survival difference between those who underwent primary or elective LMPCI and survival difference between patients based on extent of coronary artery disease. Results: A total of 73 patients underwent elective or primary left main angioplasty. The extent of coronary artery disease was: single vessel coronary artery disease (26%), double vessel coronary artery disease (37%), and three vessel coronary artery disease (37%). Thirteen patients (17.8%) had primary left main angioplasty, and 60 patients (82.2%) had elective left main angioplasty. Intravascular ultrasound was performed in only 3 patients. The mean duration of follow up was 395 days. A total of 6 (8.2%) patients died. Three patients died in-hospital, another 2 within the first 30 days, and the remaining beyond 30 days. Two of the dead patients had double vessel coronary artery disease, and 4 had three vessel coronary artery disease. The survival difference between the primary vs elective groups was insignificant (Log Rank (Mantel-Cox) (p=0.27). The survival difference between the 3 groups with different extent of coronary artery disease was insignificant (p=0.15). Conclusion: Left main PCI is a safe procedure with acceptable outcomes. Patients with more severe coronary artery disease tend to fare worse.

Background: Currently, patients with coronary artery disease are advised to use coronary stenting as their primary revascularization method. This study aims to compare outcome of MACE after DEB Vs DES in treatment of patients within stent restenosis (ISR) presented with chest pain. Methodology: The current study was Quasi experimental study carried out at the Department of Cardiology, MTI-HMC Peshawar for duration of six months from 21 April 2021 to 21 Nov 2021. In this study, 94 patients in DEB group and 94 patients in DES group were followed for 06 months to look for development of MACE.  All data was collected through a well-defined proforma. Data was entered on computer software SPSS version 22. Results: In DEB group, 52 (55.3%) male patients and 42 (44.7%) female patients were recorded whereas in DES group, 57 (60.6%) male patients while 37 (39.4%) female patients were recorded. In DEB group, 15 (16.0%) patients were recorded with MACE whereas in DES group, 38 (40.4%) patients were recorded with MACE. Conclusion: Our study showed that DEB is superior to DES in the management of in-stent restenosis and results in fewer major adverse cardiovascular events (MACE), so DEB may be considered as a treatment option for CAD patients admitted to our setting in in order to reduce mortality and morbidity associated to restenosis in such patients.