Aim: The present study aimed to compare the Sharibadi decoction which was prepared in two different ways. Sharibadi decoction A: All the ingredients are available including a local variety of H. indicus and Indian variety of H. indicus. Sharibadi decoction B: All the ingredients are available except the local variety of H. indicus and double the amount of Indian variety of H. indicus. Methodology: Phytochemical (in terms of secondary metabolites and Thin Layer Fingerprint profiles) and Physico-chemical (in terms of ash values and extractable matter) analyses were carried out to compare the Sharibadi decoction A with the Sharibadi decoction B. Results: Comparison of phytochemicals and Thin Layer Fingerprint profile of Sharibadi decoction A with that of Sharibadi decoction B revealed the differences in phytochemical compound/s presence in both decoctions. However, Physico-chemical parameters of Sharibadi decoction A were almost similar to that of Sharibadi decoction B. Conclusion: Absence of local variety of H. indicus gives an impact on phytochemical constituents rather than Physico-chemical parameters of Sharibadi decoction. However, phytochemicals play a major role when a drug exhibits its therapeutic effect/s. Therefore, to get the best therapeutic effect of Sharibadi decoction, both local variety of H. indicus and Indian variety of H. indicus should be used with other ingredients.
Background: Ayurveda is a medicinal system which has a long history which goes back to 5000 B.C. Most of the time plant based formulations are used in Ayurveda system of medicine. Chronic kidney disease has been recognized as one of the non communicable diseases in Sri Lanka. Thoravature Taila is a traditional formulation which is mentioned under the Sri Lankan Ayurveda Pharmacopeia and is recommended specially for chronic kidney disease. In ancient time, herbal medicines were standardized based on the organoleptic characters. However, such an evaluation can be vary from individual to individual and is not adequate for industries in large scale. Objective and Methods: Therefore, an attempt was made to standardize Thoravature Taila in terms of physic-chemical parameters and development of Thin Layer Chromatography (TLC). Results: Specific gravity, refractive index, peroxide value, acid value, saponification value iodine value for Thoravature Taila were 0.9580 ± 0.0004, 1.3846± 0.0012, 6.4±0.5 milliequalents/kg, 0.4±0.0 mg KOH/g, 325.5±1.2 mg KOH/g, 16.2± 0.4 g I2100/g respectively. TLC fingerprint of Thoravature Taila was developed using ethyl acetate, methanol, cyclohexane and dichloromethane in a ratio of 0.2:0.2:1.6:3.0 v/v and observed under 254 nm and 366 nm. Conclusion: analytical data such as specific gravity, refractive index, peroxide value, acid value, saponification value and iodine value and TLC fingerprint were developed for Thoravature Taila for the first time and can be considered as the standard parameters when assessing the quality of this medicated oil.
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