Introduction: Stevens-Johnson syndrome (SJS) is caused by a delayed immune response triggered by the association of genetic and environmental factors. This reaction can be mediated mainly by some drugs. Objective: The purpose of this article is to report the case of a patient with SJS associated with carbamazepine. Case report: A man was hospitalized complaining of odynophagia, whitish plaques in the mouth and swelling of the lips. Clinical examination revealed ulcerated and erosive lesions involving the buccal mucosa, lips, tongue and hard palate. The lips were swollen and with hemorrhagic crusts. Papular and purplish-colored lesions were observed on the skin. The patient reported that the lesions started 10 days ago, coinciding with the start of carbamazepine use. The diagnosis of SJS was established based on clinical information and the patient treated with support therapy. Conclusion: SJS is a clinical condition that affects the oral mucosa and can be triggered by the use of carbamazepine.
Anatomical anomalies in the salivary glands, such as ductal ectasia and stenosis, are rare and can be idiopathic, congenital, or acquired. The diagnosis of these anomalies is based on imaging examinations and is sometimes challenging. A 65-year-old female patient complained of a recurrent volume increase in the right preauricular region for 43 years. The swelling was exacerbated during the periprandial period. Physical examination with palpation revealed a flaccid swelling. Aspiration showed clear liquid compatible with saliva. Ultrasonography and magnetic resonance (MR) sialography showed changes in ductal anatomy and sialocele. MR sialography allowed the diagnosis of sialocele secondary to idiopathic duct anomalies, ectasia, and strictures in the parotid ducts. The treatment was sialoendoscopy. The patient presented a good clinical evolution with a significant reduction in swelling in the preauricular region due to less saliva accumulation. Sialoendoscopy is an effective method for the diagnosis and treatment of major salivary gland anomalies.
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