Basal-cell carcinoma with perineural invasion is a rare occurrence. Ten patients with this phenomenon are described. Review of our cases and cases in the literature indicates that perineural spread of basal-cell carcinoma is most common in men with recurrent tumors. The horizontally cut frozen sections that are utilized in Mohs surgery maximize the chances of discovering basal-cell carcinoma with undiagnosed involvement.

No abstract

Benign dermatologic conditions are no longer treated with therapeutic radiation because of the late complications that can result. One of the most serious complications that may occur is the development of skin cancer of various types. In this report, a patient received radiation for hypertrophic tonsils and later developed basal-cell carcinomas in the irradiated areas.

In brief: Fifty-one female professional golfers and 142 female amateur golfers were evaluated for skin cancer and skin cancer risk. The professionals were considerably younger than the amateurs (average of 28.4 vs 54.5 years) and received five times as much sun exposure as the amateurs. Four of the professionals had already developed basal cell carcinoma (BCC). Their average age was 25.5 years. Eleven amateurs also developed BCC, but their average age was 51.4 years. This study suggests that skin cancer can develop at earlier ages when sun exposure has been heavy. The likelihood of developing a skin I cancer also was related to eye and hair color.