No abstract

Introduction. Allergen-specific IgE (sIgE) testing provides an objective assessment of sensitization to an allergen. Goal. To identify the time when serum measurements of sIgE would be most sensitive. Methods. This was a prospective study conducted between September 1, 2015, and February 25, 2019. Subjects ≥5 and ≤18 years of age, seen in the ED or admitted with an asthma exacerbation, were tested for total IgE and 8 perennial sIgE levels. Subjects with elevated sIgE were tested again after symptom resolution. Results. A total of 104 subjects were enrolled; 50 subjects were eligible for inclusion in the analysis. There were statistically significant differences between the visits for all sIgE, except Alternaria alternatum. Conclusions. In pediatric patients, serum sIgE levels measured during an asthma exacerbation were elevated compared with when their asthma was in better control. sIgE testing during an asthma exacerbation may help identify asthma triggers, mitigate exposure, and hence improve asthma control.

a preponderance of high-risk behaviors (elevated number of sexual partners and the absence of barrier protection during intercourse). This study highlights the critical need for targeted intervention programs aimed at reducing sexual risk behavior, as well as, illicit drug use with this high-risk population. Sources of Support: No outside support.

4o6 UZDI4JV CORRESPONDENCE. [SEPT. iz, glz6 nIhildrcu under 1 year of age was 3.5 per 1,000, as compared with 4.1 of the previous year; 695 deatlhs were registered as due to the zymotic diseases, and tllis cotnpares very favourably withl 1,107 in 1914. Typlhoid fever uised to carry off its hiundreds yearly; only 10 proved fatal in 1915. rlie national schools, numbering 292, were regularly inspected, but as botlh male, female, and infants are occasio.ally under. the same roof, there are not so nany buildings. Allowing 10 square feet for each pupil, according to tlho regulations of tlhe Commissioners for INa.tional Edducation, tlhero is accommodation in these scllools for 58,500 pupils; the number on the roll during thle year was 65,649, while thc average attendance was 49,964. Twenty-five schools weFe found to be overcrowded on eaclh inspection, and 118 occasionally.