El presente estudio tuvo por objetivo describir las características clínicas, manejo y mortalidad de pacientes adultos hospitalizados por COVID-19 durante la primera quincena de mayo del 2020 en el Hospital Nacional Edgardo Rebagliati Martins (Lima, Perú). Se realizó una cohorte retrospectiva revisando historias clínicas electrónicas. Se recolectaron datos de 152 pacientes (68,4% varones, edad promedio: 58,7 años). Se encontró que 27,0% tuvo contacto cercano con una persona con COVID-19, 64.2% llegó al hospital con una enfermedad crítica, 91,4% recibió hidroxicloroquina y 96,1% recibió azitromicina, 23,7% ingresó a la unidad de cuidados intensivos, y la mortalidad fue de 18,8%. En conclusión, más de la mitad de los pacientes acudieron a este hospital con una enfermedad crítica, casi todos recibieron fármacos que inicialmente fueron vistos como potencialmente útiles pero que actualmente no son recomendados para el manejo de COVID-19 en hospitalizados, y la mortalidad fue similar a lo reportado en otros países.
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Hyperplastic polyps are the most frequent benign epithelial gastric polyps. Although they are considered nonneoplastic, some cases have been reported with focal adenocarcinoma. We present the case of a 59-year-old woman with a sessile lesion of 15 mm on the distal gastric body associated with an extensive atrophic gastritis. Magnifying endoscopy with Fuji Intelligent Color Enhancement (FICE) revealed an irregular microsurface pattern at the apex, suggesting malignancy. A mucosectomy was performed. The histopathology revealed that the base corresponded to a hyperplastic polyp, where a tubular adenoma with high-grade dysplasia was established, with focal well-differentiated intramucosal tubular adenocarcinoma.
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