Objective: This paper aims to explore the scientific literature in order to show how the process of institutionalizing (incorporating) the ‘sustainability’ of the performance evaluation system (PES) contributes to organizational performance management (OPM). Methodology: An integrative review was carried out with the support of the ProKnow-C intervention instrument to select 39 articles that formed part of the bibliographic portfolio (BP). The PB analysis was conducted through the evolution of the performance evaluation (PE) area; the elaboration of the concept of OPM, which guided this research; and the development of a ‘lens’ using the concept of the ‘sustainability’ of the PES, from which it was possible to identify its essential aspects and use them as a basis for exploration. With this, it was feasible to demonstrate the relationship of the ‘lens’ with the guiding concept that allowed the elaboration of a taxonomy. Findings: In terms of the results, the evolution of a mature theme in the literature (PE) from a new perspective and with an emphasis on the integration of elements related to management is presented, allowing for the identification that the management elements are incipient and little developed in the literature. The elaboration of a taxonomy made it possible to verify that ‘learning’ is the aspect of sustainability that most contributes to OPM, that the ‘holistic/integrated vision’ element encompasses all aspects that determine the sustainability of the PES, and that the ‘use of information’ is the common component and link between the sustainability of PES and OPM in promoting organizational learning, supporting communication and providing it with a foundation for decision-making. Originality: Gaps were identified in the literature that led to the elaboration of a future research agenda for questions related to the importance of culture in encouraging the continuous process of performance management, the relationship of organizational learning with the context and strategic alignment, and the contribution of the human factor and culture to the continuous improvement of organizational performance. Thus, this research offers a new guiding perspective for OPM.

CONCLUSIONSLE and APS may present with thrombocytopenia, but in both cases, a good response to treatment with corticosteroids and immunosuppressants would be expected, which did not occur with the patient mentioned in the case. Thrombocytopenia in cirrhosis liver is usually primarily due to decreased hepatic production of thrombopoietin rather than splenic sequestration. However, this was also not observed in the present case as platelets reached normal levels after splenectomy. Therefore, thrombocytopenia was due to splenic sequestration, resulting from cirrhosis.

BACKGROUNDInfection can be a threat to systemic lupus erythematosus (SLE) patients who have compromised immune system, being considered one of the most common causes of mortality in SLE, both by immunological factors of the disease itself or by suppressive treatment. Tuberculosis (TB) has a prevalence of 5 to 30% in patients with SLE, mainly in the extrapulmonary forms with more extensive pulmonary involvement, and a higher relapse rate. The aim of this study is to report cases of patients with SLE and TB infection treated in a tertiary hospital. METHODSThis retrospective study included cases of SLE and concomitant pulmonary, extrapulmonary and disseminated TB infection. Patient data was processed to extract information such as age, sex, time of illness, disease activity, and immunosuppressive treatment. RESULTSThe observed result showed a total of 28 patients, of which 26 received confirmation of the bacteriological diagnosis by Molecular Rapid Test for TB (MRT-TB) or smear microscopy during the investigation of the underlying disease activity. Two patients received empirical diagnosis due to highly suggestive clinical manifestation. The mean age of patients was 28.3 years. The female:male ratio in this sample was 27:1. The mean time of lupus diagnosis was 5.19 years and the main disease activity was 67% renal involvement. The other underlying disease activity was hematological, serositis, neurological and interstitial lung disease. It could be seen in the medical records that urinary and pulmonary TB was the most frequent infection in these patients, seven cases each. The second prevalent territory was TB in the central nervous system in six patients, followed by pleural and peritoneal TB, with four and three patients, respectively. There was also a diagnosis of joint, pericardial and intestinal TB. It was observed in the medical records that five patients were diagnosed with disseminated TB, presenting positive MRT-TB in two or more territories. All 28 patients were receiving corticosteroids; six of them had recent pulse therapy with methylprednisolone; six of them receiving mycophenolate mofetil; two patients receiving azathioprine; one patient was receiving cyclophosphamide and the other rituximab. CONCLUSIONTB remains a public health problem in Brazil. A clinical distinction between infection and lupus flare-up is required when patients with SLE present fevers or other infection symptom. Diagnosis should be suspected in patients investigating disease activity or in use of high-dose glucocorticoids and immunosuppressant, although differentiating between infection and disease activity is a dilemma in SLE.

Objetivo: Relatar um caso de fibrodisplasia ossificante progressiva (FOP), diagnosticado na infância, descrever características marcantes da doença e reforçar a importância do diagnóstico precoce e manejo preventivo adequado. Detalhamento do caso: Paciente de 7 anos de idade, pardo, sexo masculino, aparentemente saudável até os seis anos de idade, evoluindo há aproximadamente 1 ano com múltiplas nodulações em região dorsal, inicialmente de consistência fibroelástica, móveis e dolorosas, com posterior e gradativo enrijecimento das partes afetadas e resolução do quadro álgico associado. Destacava-se limitação funcional, com redução de mobilidade do esqueleto axial. A coluna vertebral apresentava-se com focos de ossificações ectópicas na musculatura paravertebral. Havia ainda má formação do hálux bilateralmente, que se apresentavam reduzidos de tamanho e em valgismo. Os exames laboratoriais não mostraram alterações, exceto elevação de fosfatase alcalina. As radiografias evidenciavam calcificações heterotópicas em regiões cervical e dorsal. Considerações finais: Apesar de descoberta há mais de 300 anos, o conhecimento geral sobre a FOP avançou pouco. A divulgação de trabalhos como este, contribui para que os pacientes sejam cada vez menos expostos a procedimentos desnecessários, recebam diagnóstico precoce, educação sobre a doença e tratamento de suporte, minimizando assim, os impactos sobre sua qualidade de vida.

BACKGROUNDThe epidemiology of primary Sjögren's syndrome (pSS) has been the subject of recent study in America, Africa, Asia and Europe. Previous reports show several variable data. The objective of this study was to describe the epidemiological and clinical profile of patients with pSS. METHODSThis is a cross-sectional and descriptive epidemiological study of patients treated at a university hospital. Data of patients with pSS diagnosis according to the American College of Rheumatology/European League Against Rheumatism Classification Criteria 2016 (ACR/EULAR 2016) were analyzed at Statistical Package for the Social Sciences (SPSS) program. RESULTSTwenty-six patients were included: 96.2% women, 76.9% mixed race, 15.4% white, 47.92 ± 11.83 years old. Analyzing the clinical profile, 84.6% reported at least one symptom related to ocular dryness, 80.8% oral dryness, 100% anti-Ro/SSA, 61.5% anti-La/SSB. Within the 22 patients tested for ANA, 18 were positive, and of the 17 tested for RF, 10 were positive. Of the total number of patients,