AIM: Mineral trioxide aggregate (MTA) was associated to Aloe vera to verify the coadjutant action of that medicinal plant in the bone neoformation process in tibia of rats.MATERIAL AND METHOD: 36 male rats (Rattus norvegicus) were used, divided into two groups of 18 rats each. Two circumferential bone defects with approximately 5 mm in diameter were made on the right tibia of each animal: the upper defect was filled with blood coagulates in both groups to serve as experimental control and the lower defect was filled with MTA and Aloe vera in experimental (group E1) and MTA and distilled water in experimental (group E2). Seven, 15 and 30 days after surgery, six animals from each group were euthanized and the right tibia of each animal was removed for histological analysis.RESULT: Histologically, experimental group E1 presented better results for the two variables, inflammation [at seven days (p=0.045)] and bone formation [at seven days (p=0.018) and 30 days (p=0.034)], compared to the E2 group.CONCLUSION: The association of MTA and Aloe vera showed potential to reduce the effects of the inflammatory cascade and promote bone neoformation making it to a promising proposal for future use in endodontic therapy.

Objective: This study aimed to test the calcium hydroxide associated with vehicles Aloe vera, chlorhexidine digluconate (2%) and saline, in inhibiting bacterial growth on Mueller-Hinton agar plates. Methods: The species Staphiloccocus aureus, Streptococcus pyogenes, Escherichia coli and Enterecoccus faecalis were isolated and inoculated in 3 mL of BHI (Brain Heart Infusion). Holes (5 mm diameter) were made in the plates and filled with the test materials. After incubation, readings were taken with a hand lens and a caliper with 0.1 mm accuracy to determine the diameter of the inhibition zone, after 24 and 48 hours. Each experiment was repeated six times, and the average values were obtained. Results: Chlorhexidine digluconate without calcium hydroxide resulted in better inhibition of bacterial growth, followed by the hydroxide pastes evaluated. E. coli strains were the most resistant to the tested compounds, followed by S. pyogenes and S. aureus. There was no statistically significant interaction between the variables. Conclusion: Chlorhexidine digluconate (2%) alone showed the best antimicrobial effectiveness. Aloe vera is a promising vehicle for the calcium hydroxide but more studies should be conducted on herbal medicines in dentistry.

RESUMOO ameloblastoma é um tumor odontogênico benigno, porém agressivo, de origem epitelial, constituindo cerca de 1-3% de todos os tumores e cistos da mandíbula. Apresenta crescimento lento e persistente, localizado na maior parte dos casos na área de ramo de mandíbula e ocasionalmente associado com terceiros molares inclusos. As lesões são caracterizadas por uma infiltração agressiva para o tecido adjacente e as células tumorais restantes podem levar a morbidades múltiplas de recorrência. Dessa forma, pode ocorrer uma elevada taxa de recorrência local se não for adequadamente removido. Este artigo relata um caso de ameloblastoma multicístico previamente tratado com terapia conservadora que resultou no insucesso do tratamento e recidiva da lesão após oito anos. O exame clínico demonstrou extensa reabsorção óssea na região de hemimandíbula direita. Foi realizada biópsia incisional e exame histopatológico para confirmação diagnóstica. O tratamento proposto foi a ressecção total em bloco envolvendo além de hemimandíbula direita, a região de elementos dentários 31 e 32 com margem de segurança de dois centímetros. O protocolo radical cirúrgico com boa margem de segurança deve ser a opção para prevenir a recidiva destes tumores agressivos.