Background
Social capital has been linked to health behaviours, but the underlying mechanism is unclear. Previous studies have found that health literacy played the role of a mediator in the relationships among social capital, individual physical activity and nutrition. But it is not clear whether eHealth literacy mediates the impact of social capital on health behaviours. Therefore, our research aimed to explore the relationships among social capital (structural and cognitive social capital), eHealth literacy, and the health behaviours of elderly people, and to analyse the mediating effect of eHealth literacy, while providing a theoretical basis for a health behaviour intervention for elderly people.
Methods
From January to February 2019, we conducted a cross-sectional survey of 1201 Chinese people aged over 60 years using the Chinese Shortened Social Capital Scale (contains two subscales of structural social capital and cognitive social capital), eHealth Literacy Scale, and Health-Promoting Lifestyle Profile. We used structural equation modelling to test a hypothetical mediation model.
Results
The mean scores of social capital was 72.07 (SD = 13.03), 17.24 (SD = 9.34) for eHealth literacy, and 112.23 (SD = 23.25) for health behaviours. Social capital and eHealth literacy were significantly correlated with health behaviours, and social capital and structural social capital were significantly correlated with eHealth literacy. Lastly, eHealth literacy mediated the relationship between structural social capital and health behaviours.
Conclusions
eHealth literacy was an important mediating factor for elderly people’s structural social capital and health behaviours. Therefore, social capital and eHealth literacy must be considered when designing and implementing health behaviour intervention programmes for elderly people.
We have developed an efficient formylation
of pyrroloisoquinolines
using bromoisobutyrate and dimethyl sulfoxide as carbonyl reagent.
Various formylated pyrroloisoquinolines could be prepared in good
yields (up to 94%). This formylation process can be easily scaled
up to gram scale with good yield. In most cases of pyrroloisoquinolines
without methoxy groups, the combination of bromoisobutyrate and dimethyl
sulfoxide could act as a bromination reagent, delivering brominated
pyrroloisoquinolines in acceptable to good yields (up to 82%).
An efficient methylthiomethylation
of pyrroloisoquinolines and
pyrroloquinolines has been reached by the use of ammonium acetate
and dimethyl sulfoxide. Methylthiomethylated heterocycles can be obtained
in moderate to good yields in most cases, while trace amounts to good
yields of methylene-bridged products can be observed. Choice of DMSO
activator and its amount have a great influence on the chemoselectivity
of this process. It is worth noting that this process can also be
scalable. Another feature of this process is that the product can
be transformed to sulfone and sulfoxide easily.
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