Recently, there has been a significant growth of interest in applying software engineering techniques for the quality assurance of deep learning (DL) systems. One popular direction is deep learning testing, where adversarial examples (a.k.a. bugs) of DL systems are found either by fuzzing or guided search with the help of certain testing metrics. However, recent studies have revealed that the commonly used neuron coverage metrics by existing DL testing approaches are not correlated to model robustness. It is also not an effective measurement on the confidence of the model robustness after testing. In this work, we address this gap by proposing a novel testing framework called Robustness-Oriented T esting (RobOT). A key part of RobOT is a quantitative measurement on 1) the value of each test case in improving model robustness (often via retraining), and 2) the convergence quality of the model robustness improvement. RobOT utilizes the proposed metric to automatically generate test cases valuable for improving model robustness. The proposed metric is also a strong indicator on how well robustness improvement has converged through testing. Experiments on multiple benchmark datasets confirm the effectiveness and efficiency of RobOT in improving DL model robustness, with 67.02% increase on the adversarial robustness that is 50.65% higher than the state-of-the-art work DeepGini.

No abstract

Due to their beneficial effects on human health, antioxidant peptides have attracted much attention from researchers. However, the structure-activity relationships of antioxidant peptides have not been fully understood. In this paper, quantitative structure-activity relationships (QSAR) models were built on two datasets, i.e., the ferric thiocyanate (FTC) dataset and ferric-reducing antioxidant power (FRAP) dataset, containing 214 and 172 unique antioxidant tripeptides, respectively. Sixteen amino acid descriptors were used and model population analysis (MPA) was then applied to improve the QSAR models for better prediction performance. The results showed that, by applying MPA, the cross-validated coefficient of determination (Q2) was increased from 0.6170 to 0.7471 for the FTC dataset and from 0.4878 to 0.6088 for the FRAP dataset, respectively. These findings indicate that the integration of different amino acid descriptors provide additional information for model building and MPA can efficiently extract the information for better prediction performance.

No abstract

No abstract