Nitric oxide (NO) shows high potential in the cardiovascular system with anticoagulant and antibacterial efficacy.

Naked medical devices are often damaged by blood, bacteria, and other extreme environmental conditions (heat, humidity, acid, alkali, salts, and others), causing device failure and increasing difficulty for the operator. They can also cause inflammation and coagulation resulting in severe complications and even death. In this work, the superhydrophobic ZnO/copper−zinc metal−organic frameworks@stearic acid (ZnO/Cu−ZnMOFs@SA) composite coatings with hierarchical micro/nanostructures were fabricated on Zn substrates via a one-step hydrothermal method. The effects of hierarchical micro/nanostructures on surface wettability, physicochemical stability, and biological properties have been studied in this manuscript. The structure not only provided the coatings with robust waterproofing, abrasive resistance, durability, and thermal and light irradiation stability but also successfully recovered their superhydrophobicity by remodifying the surface with SA, showing excellent repeatability. In addition, the coating demonstrates excellent corrosion resistance and self-cleaning ability and rejects various solid and liquid contaminants. The superhydrophobic ZnO/Cu−ZnMOFs@SA composite coatings also exhibited excellent antibacterial and thrombosis resistance. The findings indicated that the superhydrophobic composite coatings have a strong potential for application in medical instruments for exhibiting multifunctional properties in various extreme environments.

The anticoagulation and antibacterial functions of implant and interventional catheters during indwelling will determine the success or failure. Here, an amino-containing copper based metal organic frameworks (Cu-MOFs) coating was prepared...

Surgical devices inevitably come into contact with blood, bacteria, high temperatures, high humidity, and acidic, basic, and salt environments during use, which can have a significant impact on the device and the operator, so their protection becomes necessary. In this manuscript, novel, highly robust, and superhydrophobic Ni-doped ZnO–ZnS@stearic acid (SA) composite films with extreme repellency to various solid and liquid contaminants, excellent bactericidal performance, and extremely low blood adhesion were fabricated by a simple one-step hydrothermal method. Additionally, the synergistic effect of the in situ generated hierarchical micro/nanocomposite structures on the Zn substrate surface and SA also endowed the film with excellent mechanical and chemical stability, such as ultra-low adhesion, perfect wear resistance, corrosion resistance, heat resistance, and good durability. Notably, the superhydrophobic composite films could be turned into a superhydrophilic film by simple heat treatment. Further, it could revert to its superhydrophobic state by remodification of stearic acid. This unique structure and low surface energy SA modification were found to be the primary reasons for the excellent protection and versatility of galvanized surgical devices in various extreme environments.