Real-time glucose monitoring conventionally involves non-bioresorbable semi-implantable glucose sensors, causing infection and pain during removal. Despite bioresorbable electronics serves as excellent alternatives, the bioresorbable sensor dissolves in aqueous environments with interferential biomolecules. Here, the theories to achieve stable electrode potential and accurate electrochemical detection using bioresorbable materials have been proposed, resulting in a fully printed bioresorbable electrochemical device. The adverse effect caused by material degradation has been overcome by a molybdenum-tungsten reference electrode that offers stable potential through galvanic-coupling and self-compensation modules. In vitro and in vivo glucose monitoring has been conducted for 7 and 5 days, respectively, followed by full degradation within 2 months. The device offers a glucose detection range of 0 to 25 millimolars and a sensitivity of 0.2458 microamperes per millimolar with anti-interference capability and biocompatibility, indicating the possibility of mass manufacturing high-performance bioresorbable electrochemical devices using printing and low-temperature water-sintering techniques. The mechanisms may be implemented developing more comprehensive bioresorbable sensors for chronic diseases.

Smart wound dressings supply new techniques for wound management. Nevertheless, techniques to combine microenvironment control of the wound beds and spontaneous release of antibacterial agents while reducing secondary injury of the wound due to frequent replacement of wound dressings have not been sufficiently developed. Herein, this work proposes a degradable and flexible skin patch that can assist wound healing through the combined effect of thermostatic control, slow release of antibacterial metallic ions, and humidity control. The skin patch features a degradable zinc-silver (Zn-Ag) gird line heater and a Zn temperature sensor fabricated through screen printing and water sintering. The sintered degradable patterns of Zn-Ag and Zn offer electrical conductivities of 307664.4 and 72400 S m −1 , enabling closed-loop thermostatic control of the wound under a temperature range of 43 ± 2 °C. The gradual degradation of the nanocomposites in a humid environment results in an antibacterial effect with more than 99% antibacterial efficiency (AE) on the wound site due to the release of Ag and Zn ions. The skin patches are demonstrated to improve wound healing in rats and rabbits by 18.35% and 51.57%, respectively. The flexible skin patch revolutionizes the wound treatment procedure by replacing traditional wound dressing with degradable materials and flexible circuits.