~The effects of rye bran, oat bran and soya-bean fibre on serum lipids, bile composition and gallstone formation were studied in male Syrian golden hamsters (Mesocvicetus auvatus). The control groups received fibre-free stone-provoking (01 diet) or non-stone-provoking ( 0 2 diet) diets. The serum cholesterol levels were lower for all groups fed on the diets supplemented with the dietary fibre sources compared with the control groups. The total content of bile acids in bile was higher in groups given ryebran diets compared with the corresponding controls. The proportion of cholic acid was higher and that of chenodeoxycholic and lithocholic acid lower in the groups given rye-bran-, oat-bran-or soya-beanfibre-supplemented diets, compared with the corresponding controls. The secondary : primary bile acid ratio was lower in the group given the rye-bran-supplemented 0 1 diet. The lithocho1ic:deoxycholic acid ratio was lower in the groups given rye-bran-, oat-bran-or soya-bean-fibre-supplemented diets than in the corresponding controls. A lower frequency of gallstones was observed only for the group receiving the rye-bran-supplemented 01 diet while the lithogenic index was lower in the groups given the rye-bransupplemented 0 2 diet. A decreased epithelial volume density of the gall-bladder and an increased smooth muscular volume density were observed in animals given oat-bran-and rye-bran-supplemented 0 1 diets, whereas for the soya-bean-fibre-supplemented 0 1 diet, only the smooth muscular volume density was increased.Rye bran: Oat bran: Soya-bean fibre: Bile: Serum lipids: Hamsters