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The previous, published data on the association between CYP1B1 polymorphisms and cancer risk remained controversial. To derive a more precise estimation of the association between the CYP1B1 polymorphisms and cancer risk, we performed a meta-analysis to investigate the association between cancer susceptibility and CYP1B1 Leu432Val, Asn453Ser, Arg48Gly, and Ala119Ser polymorphisms. For Asn453Ser and Arg48Gly polymorphisms, significantly decreased endometrial cancer was observed among Caucasians. For Ala119Ser polymorphism, we found that individuals with the minor variant genotypes had a high risk of prostate cancer. For Leu432Val polymorphism, we found that individuals with the minor variant genotypes had a higher risk of endometrial cancer and lung cancer and had a lower risk of ovarian cancer. In summary, this meta-analysis suggests that Leu432Val polymorphism is associated with ovarian cancer, lung cancer, and endometrial cancer risk; Asn453Ser and Arg48Gly polymorphisms are associated with endometrial cancer risk among Caucasians, Ala119Ser polymorphism is associated with prostate cancer risk, and Ala119Ser polymorphism is associated with breast cancer risk in Caucasians. In addition, our work also points out the importance of new studies for Ala119Ser polymorphism in endometrial cancer, because high heterogeneity was observed (I (2) > 75 %).

We collect all known intrinsic and extrinsic S-type stars to discuss their infrared properties and find their difference in the infrared using photometric data from the Two Micron All Sky Survey, Wide Field Infrared Survey Explorer, and Infrared Astronomical Satellite missions. Then we look for the diagnosis to extract intrinsic S-type stars from the large unclassified sample. We found that, statistically, intrinsic S-type stars have larger infrared excesses than extrinsic S-type stars in the wavelength region of 1–60 μm due to thicker dusty circumstellar envelopes. We also found that only intrinsic S-type stars occupy the reddest color areas in all of the two-color diagrams we presented. Finally, 172 new intrinsic S-type stars are presented in this paper. This makes the number of known intrinsic S-type stars almost double. In addition, some intrinsic and extrinsic S-type stars have power-law distributions in some two-color diagrams with the wavelength longer than 5 μm. The possible reason for this is also discussed.