Graft and dendronized polymers have attracted much attention in the polymer community, and there have been significant efforts to develop better synthetic methods. Herein, we report the highly efficient synthesis of graft and dendronized polymers by using Cu-catalyzed multicomponent polymerization (MCP). Based on diversity-oriented synthesis, we prepared a library of various graft and dendronized polymers from combinations of three types of monomers (mono-functionalized alkynes, bis-sulfonyl azides, and diamines/diols) that are bench stable and readily accessible. After reaction optimization, 54 samples of high-molecular-weight graft and dendronized polymers were prepared, the MCP method allowing simultaneous manipulation of the structures of both the main chains and the side chains. Moreover, because of the severe steric hindrance of the side chains, these polymers adopted extended conformations, as shown by the large shape parameter in solution. Also, the extended morphology of the single polymer chains was directly visualized by atomic force microscopy and transmission electron microscopy in the solid state. Most importantly, this diversity-oriented polymerization became possible because of highly step-economical and efficient one-step MCP, paving the way toward the easily tunable synthesis of graft and dendronized polymers.

We demonstrate the first example of cascade polymerization by combining olefin metathesis and metallotropic 1,3-shift reactions to form unique conjugated polyenynes. Rational design of monomers enabled controlled polymerization, and kinetic investigation of the polymerization mechanism was conducted.

Background: Our research results will be helpful in the development of the K-beauty customized cosmetics industry as well as consumers who are having difficulty in purchasing cosmetics due to the rapid transition to a non-face-to-face society due to COVID-19. Objectives: This paper attempted to investigate the recognition and development potential of customized cosmetics, focusing on mobile shopping in the era of COVID-19 untact period. Methods: The women included in the study consumer Seoul residence in the mobile shopping experience 40-60 targets for women 380 were the people. Statistical processing of data collected by the data analysis method is analyzed using the SPSS (Statistical Package for Social Science) WIN25.0 statistical package program through the process of data coding and data cleaning.Results: As the untact era enters, the frequency of using non-face-to-face mobile shopping for customized cosmetics is increasing, and it is believed to be deeply related to the level of interest in skin and recognition of customized cosmetics, such as the use of hands-on apps that incorporate new technologies of the 4th industrial revolution. Looking at the Kaiser-Meyer-Olkin to confirm the normality and validity of the population proved its validity. January 2020 (after COVID-19 spread), the use of mobile shopping was increased. In the future, it was significantly higher to continue shopping for cosmetics using mobile devices p < 0.001. Conclusion:The present study focused on the recognition and development potential of customized cosmetics on mobile shopping in the era of COVID-19 untact period. Our results suggested that the possibility of developing customized cosmetics through mobile shopping in the untact era after COVID-19 will be endless, and it is believed that various marketing strategies will be supported in the future.

Background: Severe acute respiratory syndrome coronavirus disease 19 is attracting worldwide attention and has been declared an infectious disease by the World Health Organization (WHO), and accordingly, interest and meaning in health and well-being are expanding in recent years. Aims: This paper attempted to investigate the recognition and development potential of customized cosmetics focusing on inner beauty products through DTC (Direct to Customer) genetic testing in the era of COVID-19 pandemic. Patients/Methods: The number of women included in the survey of consumers living in Seoul metropolitan city ranged from 40 to 60, and 380 women in Republic of Korea. Statistical processing of the data collected by the data analysis method is analyzed using the Statistical Package for Social Science (SPSS) WIN25.0 statistical package program through the process of data coding and data cleansing.Results: In this study, the DTC genetic test, single, and/or combination treatment for customized inner beauty products and customized cosmetics were compared and analyzed, respectively. Accordingly, in keeping with the rapidly changing market conditions, we sought to study customized inner beauty and customized cosmetics recognition and purchasing behavior through DTC genetic testing in the unexplored era after COVID-19 pandemic. As a result, it was significantly more effective to use customized inner beauty and customized cosmetics after DTC genetic test (p < 0.001). Conclusion:This study emphasizes that after the global COVID-19 pandemic worldwide that occurred after January 2020, the definition of health persistence, wellness, and well-dying associated with beauty and cosmetology is also evolving from the DTC genetic test. In our results, it was found for the first time that the intake of customized inner beauty preparations and the use of customized cosmetics would be more effective. In the above significant research results, it is believed that research on the combinational effect of customized inner beauty products and customized cosmetics is required in the global DTC genetic testing market.