Composition, cytotoxicity and antioxidant activities of polyphenols in the leaves of star anise (Illicium verum Hook. f.

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(J. Tan). technologies for essential oil have raised concern in biology, medicine and food researches in the last few years. As common wall materials for microencapsulation, cyclodextrins (CDs) are a class of cyclic oligosaccharides normally produced from starch under the effect of the enzyme catalytic reaction [Thombre et al., 2013]. CDs are characterized by their amphiphilic structure with hydrophobic inner cavity and hydrophilic outer wall, which could embed guest molecules to form relatively stable complexes [Tian et al., 2020]. They are mainly composed of 6, 7 or 8 glucose units, known as α-, βand γ-CD, respectively [Thombre et al., 2013]. Among them, β-CD is one of the most important members and is derived from 7 d(+)-glucose units linked by α-1,4-glycosidic bonds [Thombre et al., 2013]. Comparing with other CDs, β-CD is the most frequently used CD due to the lowest price and relatively appropriate size cavity. The interest in β-CD regarding its food-related applications has been increasing since it was approved for food uses by FDA [Partanen et al., 2002]. With cavity, β-CD could act as a host and include some molecules as guests to form inclusion complexes by van der Waals and hydrophobic interaction forces, or hydrogen bonds [Deng et al., 2018]. However, the applications of β-CD are limited by its relatively low binding capacity and solubility. Therefore, the metal-organic frameworks (MOFs) with the utilization of the special structure of CDs were developed to solve the above problems. CD-MOFs are network-structure and crystalline porous materials derived from CDs and metal ions or clusters for biomedical applications [Li et al., 2017; Smaldone et al., 2010]. They have high porosity, large surface areas, and ver

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