This paper presents a novel unsupervised domain adaptation method for cross-domain visual recognition. We propose a unified framework that reduces the shift between domains both statistically and geometrically, referred to as Joint Geometrical and Statistical Alignment (JGSA). Specifically, we learn two coupled projections that project the source domain and target domain data into lowdimensional subspaces where the geometrical shift and distribution shift are reduced simultaneously. The objective function can be solved efficiently in a closed form. Extensive experiments have verified that the proposed method significantly outperforms several state-of-the-art domain adaptation methods on a synthetic dataset and three different real world cross-domain visual recognition tasks.

This paper proposes an importance weighted adversarial nets-based method for unsupervised domain adaptation, specific for partial domain adaptation where the target domain has less number of classes compared to the source domain. Previous domain adaptation methods generally assume the identical label spaces, such that reducing the distribution divergence leads to feasible knowledge transfer. However, such an assumption is no longer valid in a more realistic scenario that requires adaptation from a larger and more diverse source domain to a smaller target domain with less number of classes. This paper extends the adversarial nets-based domain adaptation and proposes a novel adversarial nets-based partial domain adaptation method to identify the source samples that are potentially from the outlier classes and, at the same time, reduce the shift of shared classes between domains.

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In radiomics studies, researchers usually need to develop a supervised machine learning model to map image features onto the clinical conclusion. A classical machine learning pipeline consists of several steps, including normalization, feature selection, and classification. It is often tedious to find an optimal pipeline with appropriate combinations. We designed an open-source software package named FeAture Explorer (FAE). It was programmed with Python and used NumPy, pandas, and scikit-learning modules. FAE can be used to extract image features, preprocess the feature matrix, develop different models automatically, and evaluate them with common clinical statistics. FAE features a user-friendly graphical user interface that can be used by radiologists and researchers to build many different pipelines, and to compare their results visually. To prove the effectiveness of FAE, we developed a candidate model to classify the clinical-significant prostate cancer (CS PCa) and non-CS PCa using the PROSTATEx dataset. We used FAE to try out different combinations of feature selectors and classifiers, compare the area under the receiver operating characteristic curve of different models on the validation dataset, and evaluate the model using independent test data. The final model with the analysis of variance as the feature selector and linear discriminate analysis as the classifier was selected and evaluated conveniently by FAE. The area under the receiver operating characteristic curve on the training, validation, and test dataset achieved results of 0.838, 0.814, and 0.824, respectively. FAE allows researchers to build radiomics models and evaluate them using an independent testing dataset. It also provides easy model comparison and result visualization. We believe FAE can be a convenient tool for radiomics studies and other medical studies involving supervised machine learning.

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