This Review focuses on the current research advances of the synthesis of various amphiphilic block copolymers (ABCs), such as conventional ABCs and newly presented polyprodrug amphiphiles, and the development of corresponding self‐assemblies in selective solvents driven by the intermolecular interactions, like noncovalent hydrophobic interactions, π–π interactions, and hydrogen bonds, between ABCs or preformed small polymeric nanoparticles. The design of these assemblies is systematically introduced, and the diverse examples concerning the unique assembly structures along with the fast development of their exclusive properties and various applications in different fields are discussed. Possible perspectives on the existential challenges and glorious future are elucidated finally. It is hoped that this Review will provide a convenient way for readers to motivate more evolutional innovative concepts and methods to design next generation of novel polymeric nanoassemblies, and fill the gap between material design and practical applications.

It has been widely accepted that covalently framed nanoparticles showed extended circulation time in the blood due to their large stable structures compared to the free linear polyprodrugs. Herein, an...

Bacterial induced wound infection is very common in real life, but the abuse of antibiotics brings a potential threat to human health. The development of non-antibiotic type antibacterial materials appears...