Magnoliaceae plants are industrial tree species with high ornamental and medicinal value. We published six complete chloroplast genomes of Magnoliaceae by using Illumina sequencing. These showed a typical quadripartite structure of angiosperm and were 159,901–160,008 bp in size. A total of 324 microsatellite loci and six variable intergenic regions (Pi > 0.01) were identified in six genomes. Compared with five other genomes, the contraction and expansion of the IR regions were significantly different in Manglietia grandis. To gain a more thorough understanding of the intergeneric relationships in Magnoliaceae, we also included 31 published chloroplast genomes of close relative species for phylogenetic analyses. New insights into the intergeneric relationships of Magnoliaceae are provided based on our results and previous morphological, phytochemical and anatomical information. We suggest that the genus Yulania should be separated from the genus Michelia and its systematic position of should be restored; the genera Paramichelia and Tsoongiodendron should be merged into the genus Michelia; the genera Pachylarnax and Parakmeria should be combined into one genus. These findings will provide a theoretical basis for adjusting the phylogenetic position of Magnoliaceae at the molecular level.

Herein, we present a copper-mediated C4-benzylation of 5-aminopyrazoles with 3-indoleacetic acids. Various benzylated 5-aminopyrazoles are prepared in good-to-excellent yields under basic and ligand-free conditions in the presence of copper acetate. Moreover, this benzylation method is applicable to other substrates, including naphthylamine, 2-aminochromen-4-one, and enamines. Some products exhibit antiproliferative activities against cancer cell lines. In addition, the C4-benzylated products are cyclized into 1H-pyrazolo[4′,3′:6,7]azepino[3,4-b]indoles with aldehydes via one-pot two-step processes; notably, the cyclized products exhibit fluorescence emissions with large Stokes shifts.

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We herein describe a C4 sulfonylmethylation of pyrazol-5-amines with glyoxylic acid and sodium sulfinates. The reaction only needed to add water as the solvent, and it featured mild reaction condition,...

The Magnoliaceae plants are industrial tree species with high medicinal value. We published the 6 complete chloroplast genomes of the family Magnoliaceae by using Illumina sequencing. These 6 chloroplast genomes showed a typical quadripartite structure of angiosperm and were 159,901 − 160,008 bp in size, respectively. A total of 324 microsatellite loci and 6 variable intergenic regions (Pi > 0.01) were identified in 6 genomes. Compare with other 5 genomes, the contraction and expansion of the IR regions were significantly different in Manglietia grandis. For having more thorough understanding of the intergeneric relationship of family Magnoliaceae, we also included 31 published chloroplast genomes of close relative species for phylogenetic analyses. The new insights into intergeneric relationship of family Magnoliaceae was provided based on the combination of our result and the previous morphological, phytochemical and anatomygical information. We suggest that the genus Yulania should be separated from the genus Michelia, and restore systematic position of the genus Yulania; the genera Paramichelia and Tsoongiodendron should be merged into the genera Michelia; the genera Pachylarnax and Parakmeria should be combined into one genus. These findings will provide a theoretical basis for adjustment phylogenetic position of family Magnoliaceae at the molecular level.