It is well known that fish caudal fins can be completely regenerated after fin amputation. Although much research on fin regeneration has been carried out, there have been very few reports regarding fin regeneration after tail amputation. In this study, we used grass carp, common carp, koi carp, and zebrafish as experimental organisms. Some caudal fins could be distinctly regenerated in 2 weeks after tail amputation. After all-trans-retinoic acid treatment and tail amputation, zebrafish were unable to regenerate caudal fins that could be seen with the naked eye. However, after tail amputation, more than half of the zebrafish tested were able to regenerate caudal fins. Caudal fin regeneration depended on the presence of musculature and endoskeleton at the site of amputation. These caudal fins arose from segments of the endoskeleton, which contrast with currently accepted knowledge.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.