Single-walled carbon nanotubes (SWNTs) with various unique properties have attracted great attention in cancer theranostics. Herein, SWNTs are coated with a shell of polydopamine (PDA), which is further modified by polyethylene glycol (PEG). The PDA shell in the obtained SWNT@PDA-PEG could chelate Mn2+, which together with metallic nanoparticulate impurities anchored on SWNTs offer enhanced both T1 and T2 contrasts under magnetic resonance (MR) imaging. Meanwhile, also utilizing the PDA shell, radionuclide 131I could be easily labeled onto SWNT@PDA-PEG, enabling nuclear imaging and radioisotope cancer therapy. As revealed by MR & gamma imaging, efficient tumor accumulation of SWNT@PDA-131I-PEG is observed after systemic administration into mice. By further utilizing the strong near-infarared (NIR) absorbance of SWNTs, NIR-triggered photothermal therapy in combination with 131I-based radioisotope therapy is realized in our animal experiments, in which a remarkable synergistic antitumor therapeutic effect is observed compared to monotherapies. Our work not only presents a new type of theranostic nanoplatform based on SWNTs, but also suggests the promise of PDA coating as a general approach to modify nano-agents and endow them with highly integrated functionalities.

It is shown that analyses at the electroweak scale can be significantly affected due to Landau pole effects in certain regions of the parameter space. This phenomenon arises because of a large magnification of errors of the input parameters mt, aG which have currently a 10% uncertainty in their determination. The influence of the Landau pole on the constraint that the scalar SUSY spectrum be free of tachyons is also investigated. It is found that this constraint is very strong and eliminates a large portion of the parameter space. Under the above constraint the trilinear soft SUSY-breaking term at the electroweak scale is found to lie in a restricted domain. PACS number(s): 12.60.Jv, 04.65.+e, ll.lO.Hi, 12.10.Dm

The constraints on the minimal supergravity model from the b -+ sy decay are studied. A large domain in the parameter space for the model satisfies the CLEO bound B ( b + sy) < 5.4 x low4.However, the allowed domain is expected to diminish significantly with an improved bound on this decay. The dependence of the b -+ sy branching ratio on various parameters is studied in detail.It is found that, for At < 0 and the top quark mass within the vicinity of the center of the CDF value mF0'" = 174 i 17 GeV, there exists only a small allowed domain because the light top squark is tachyonic for most of the parameter space. A similar phenomenon exists for a lighter top and At negative when the GUT coupling constant is slightly reduced. For At > 0, however, the branching ratio is much less sensitive to small changes in mt and (YG. PACS number(s): 12.10.Dm, 04.65.+e, 13.40.Hq, 14.65.FyThe extensive analyses of the high precision data from the CERN e+e-collider LEP in the last few years have indicated that the idea of grand unification is only valid when combined with supersymmetry [I]. One of most promising and most studied models is the minimal supergravity model (MSGM) [2]. Supersymmetry (SUSY) is naturally and softly broken by a hidden sector. In addition to Yukawa couplings, the gauge coupling constant a c , and the unification scale MGUT N 10" GeV, there are only five free parameters in this model: the four soft breaking terms (the universal scalar mass mo, the universal gaugino mass m1/2, the cubic scalar coupling Ao, and the quadratic scalar coupling go), and a supersym-

It is pointed out that, besides the conventional embedding of the [Formula: see text] discrete group in the Schimmrigk model in which [Formula: see text] is embedded nontrivially, there exists an alternate embedding in which Z3 is nontrivially embedded. It is found that, for the Schimmrigk model deformed from the symmetric point by a single (2, 1)-form (z1z2z3), the deformation introduces six more nonvanishing independent (27)3 Yukawa couplings before flux breaking. The alternate embedding introduces many complex Yukawa couplings, even when the modulo is real, giving rise to automatic CP violation.