In this article, I argue that while the Global South has replaced the Third World as the prevalent term for describing structural global inequalities in International Relations, little research is directed at its theoretical implications. I discuss the conceptual evolution of the term from the Third World narrative, interpreting the literature as an implicit rejection of myopic ontologies relying on economic, cultural, or political hierarchies. I then suggest connecting the terminology to the theory of functional differentiation. By avoiding forms inherited from classical social theory, the Global South can be conceptualized in a more productive way that is better attuned to contemporary theoretical discussions.

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• Este é um artigo publicado em acesso aberto e distribuído sob os termos da AbstractIn this article, we argue that conventional understandings of regional integration based on neo-functionalism, hitherto often used to describe the diverse projects of Latin American regionalism, are of limited utility in that context. Rather than representing processes of economic or political unification, the various regionalisms could be understood more productively as a reaction to the crisis in legitimacy that social orders in the region have experienced under the conditions of globalized modernity. We then deploy an understanding of regionalism derived from sociological differentiation theory in order to advance this argument.

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