BackgroundThe evaluation of hand function impairment following a neurological disorder (stroke and cervical spinal cord injury) requires sensitive, reliable and clinically meaningful assessment tools. Clinical performance measures of hand function mainly focus on the accomplishment of activities of daily living (ADL), typically rather complex tasks assessed by a gross ordinal rating; while the motor performance (i.e. kinematics) is less detailed. The goal of this study was to develop a low-cost instrumented glove to capture details in grasping, feasible for the assessment of hand function in clinical practice and rehabilitation settings.MethodsDifferent sensor types were tested for output signal stability over time by measuring the signal drift of their step responses. A system that converted sensor output voltages into angles based on pre-measured curves was implemented. Furthermore, the voltage supply of each sensor signal conditioning circuit was increased to enhance the sensor resolution. The repeatability of finger bending trajectories, recorded during the performance of three ADL-based tasks, was established using the intraclass correlation coefficient (ICC). Moreover, the accuracy of the glove was evaluated by determining the agreement between angles measured with the embedded sensors and angles measured by traditional goniometry. In addition, the feasibility of the glove was tested in four patients with a pathological hand function caused by a cervical spinal cord injury (cSCI).ResultsA sensor type that displayed a stable output signal over time was identified, and a high sensor resolution of 0.5° was obtained. The evaluation of the glove's reliability yielded high ICC values (0.84 to 0.92) with an accuracy error of about ± 5°. Feasibility testing revealed that the glove was sensitive to distinguish different levels of hand function impairment in cSCI patients.ConclusionsThe device satisfied the desired system requirements in terms of low cost, stable sensor signal over time, full finger-flexion range of motion tracking and capability to monitor all three joints of one finger. The developed rapid calibration system for easy use (high feasibility) and excellent psychometric properties (i.e. reliability and validity) qualify the device for the assessment of hand function in clinical practice and rehabilitation settings.

Many studies have been concerned with the ancient Egyptian mummification method; nevertheless, little effort has been made to explore it experimentally. The goal of this study is to apply evidence-based diagnostic criteria and state-of-the art methodology in order to improve knowledge on soft tissues preservation and postmortem alterations. Two human lower limbs (LL) from a female donor were (1) "naturally" mummified by dry heat and (2) artificially in natron. At specific time intervals a macroscopic and radiological examination of the LL was performed and skin and muscle samples were taken for histological and biomolecular analysis. Temperature, humidity, pH, and weight of the LL were systematically measured. The mummification by dry heat was stopped after 7 days due to unexpected lack of mummification progress. The mummification in natron was completed successfully after 208 days. The humidity, the external temperature, and the pH were proven with Pearson correlation and principal component analysis as important factors for the mummification process. The steady removal of water from the tissues through the natron has prevented the putrefaction. This is also evident in the absence of bacteria or fungi through the microbiological analysis. The histological analysis revealed very good preservation of the skin and the muscle tissues. In the muscular sample certain degree of structural disintegration can be seen, particularly affecting the epimysium whilst in the skin samples the epidermis, especially the stratum corneum, is mostly affected. The samples show better preservation compared with ancient Egyptian sections and other mummified tissues from historic or forensic context. Anat Rec, 298:974-987, 2015. V C 2015 Wiley Periodicals, Inc.

Following hand function impairment caused by a neurological disorder, the functional level of the upper extremities has to be assessed in the clinical and rehabilitation settings. Current hand function evaluation tests are somewhat imprecise. Instrumented gloves allow finger motion monitoring during the performance of skilled tasks, such as grasping objects. As a result, they provide an objective tool for evaluating slight changes in the fine motor skills of the hand. Numerous gloves are based on resistive bend sensors, given that this is an easy to handle, low-cost, and reliable sensing element. When bending is not applied homogeneously along such a sensor, as is the case with finger-joint bending, its output response varies with the sensor's longitudinal position. Our goal is to determine the optimal sensor position with respect to the finger-joint in order to enhance the resolution of the sensors embedded in a glove. The validity of the integrated sensors is evaluated and the accuracy values are given. Enhancement of Bend Sensor Properties as Applied in a Glove for Use in Neurorehabilitation SettingsNinja P. Oess, Johann Wanek, and Hubertus J. A. van HedelAbstract-Following hand function impairment caused by a neurological disorder, the functional level of the upper extremities has to be assessed in the clinical and rehabilitation settings. Current hand function evaluation tests are somewhat imprecise. Instrumented gloves allow finger motion monitoring during the performance of skilled tasks, such as grasping objects. As a result, they provide an objective tool for evaluating slight changes in the fine motor skills of the hand. Numerous gloves are based on resistive bend sensors, given that this is an easy to handle, low-cost, and reliable sensing element. When bending is not applied homogeneously along such a sensor, as is the case with finger-joint bending, its output response varies with the sensor's longitudinal position. Our goal is to determine the optimal sensor position with respect to the finger-joint in order to enhance the resolution of the sensors embedded in a glove. The validity of the integrated sensors is evaluated and the accuracy values are given.