BACKGROUND AND PURPOSE
Degenerative changes are commonly found in spine imaging but often occur in pain-free individuals as well as those with back pain. We sought to estimate the prevalence, by age, of common degenerative spine conditions by performing a systematic review studying the prevalence of spine degeneration on imaging in asymptomatic individuals.
MATERIALS AND METHODS
We performed a systematic review of articles reporting the prevalence of imaging findings (CT or MR imaging) in asymptomatic individuals from published English literature through April 2014. Two reviewers evaluated each manuscript. We selected age groupings by decade (20, 30, 40, 50, 60, 70, 80 years), determining age-specific prevalence estimates. For each imaging finding, we fit a generalized linear mixed-effects model for the age-specific prevalence estimate clustering in the study, adjusting for the midpoint of the reported age interval.
RESULTS
Thirty-three articles reporting imaging findings for 3110 asymptomatic individuals met our study inclusion criteria. The prevalence of disk degeneration in asymptomatic individuals increased from 37% of 20-year-old individuals to 96% of 80-year-old individuals. Disk bulge prevalence increased from 30% of those 20 years of age to 84% of those 80 years of age. Disk protrusion prevalence increased from 29% of those 20 years of age to 43% of those 80 years of age. The prevalence of annular fissure increased from 19% of those 20 years of age to 29% of those 80 years of age.
CONCLUSIONS
Imaging findings of spine degeneration are present in high proportions of asymptomatic individuals, increasing with age. Many imaging-based degenerative features are likely part of normal aging and unassociated with pain. These imaging findings must be interpreted in the context of the patient’s clinical condition.
CAA is a rare cause of devastating neurologic symptoms and chronic pain. The imaging features of CAA range from subtle to severe. Advanced arachnoiditis can present with spinal cord swelling and syrinx formation, which can mimic other disease processes. Inclusion of advanced CAA in the differential diagnosis can prevent unnecessary interventions.
Arterial-phase three-dimensional (3D) contrast-enhanced MR angiograms of the carotid and vertebral arteries from their origins through the carotid bifurcations were obtained in 20 patients using acquisition times over 30 sec by using an MR fluoroscopy-triggered pulse sequence with elliptical centric view order. The typical pixel size was 0.8 mm (x) x 1.6 mm (y) x 1.5 mm (z), and 32-48 coronal slices were acquired. The fluoroscopic monitoring of bolus arrival was effective in 18 of the 20 cases; two failures were attributed directly to a poor choice of RF coil. To exploit peak arterial-to-venous contrast, the central 3D views were acquired first in the most compact time period possible for the given TR. For the 18 successfully triggered cases, arterial-phase 3D images were obtained with excellent venous suppression as demonstrated by an average internal jugular vein to common carotid signal enhancement ratio of only 0.05 +/- 0.04.
This retrospective observational study reveals no evidence that dexamethasone is less effective than particulate steroids in lumbar TFESIs performed for radicular pain with or without radiculopathy.
BACKGROUND AND PURPOSE:Because intramedullary spinal cord metastasis is often a difficult diagnosis to make, our purpose was to perform a systematic review of the MR imaging and relevant baseline clinical features of intramedullary spinal cord metastases in a large series.
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