CONTEXT: Coagulase-negative staphylococci are common colonizers of the human skin and have become increasingly recognized as agents of clinically significant nosocomial infections. CASE REPORT: The case of a 79-year-old male patient with multi-infarct dementia who presented systemic inflammatory response syndrome is reported. This was attributed to bacteremia due to Staphylococcus cohnii ssp. urealyticus, which was grown on blood cultures originating from an infected pressure ulcer. The few cases of Staphylococcus cohnii infection reported in the literature consist of bacteremia relating to catheters, surgical prostheses, acute cholecystitis, brain abscess, endocarditis, pneumonia, urinary tract infection and septic arthritis, generally presenting a multiresistant profile, with nearly 90% resistance to methicillin. CONCLUSIONS: The reported case is, to our knowledge, the first case of true bacteremia due to Staphylococcus cohnii subsp. urealyticus caused by an infected pressure ulcer. It shows that this species may be underdiagnosed and should be considered in the differential diagnosis for communityacquired skin infections. RESUMO CONTEXTO:Staphylococcus coagulase-negativos, colonizadores frequentes da pele humana, têm sido reconhecidos como agentes de infecções nosocomiais. RELATO DE CASO: Relata-se o caso de um paciente de 79 anos com demência vascular que apresentou síndrome da resposta inflamatória sistêmica atribuída a bacteremia por Staphylococcus cohnni ssp. urealyticus, que cresceu em hemoculturas, secundária a uma úlcera de pressão infectada. Os poucos casos de infecção por Staphylococcus cohnii relatados na literatura descrevem bacteremia associada a cateter, próteses cirúrgicas, colecistite aguda, abscesso cerebral, endocardite, pneumonia, infecção do trato urinário e artrite séptica, geralmente apresentando um perfil de multirresistência, com aproximadamente 90% de resistência à meticilina. CONCLUSÕES: O caso relatado é, ao nosso conhecimento, o primeiro de bacteremia verdadeira por Staphylococcus cohnii subsp. urealyticus causada por uma úlcera por pressão, mostrando que esta espécie pode estar subdiagnosticada e deveria ser considerada no diagnóstico diferencial das infecções cutâneas adquiridas na comunidade.
-Context -Liver cirrhosis patients with hepatocellular carcinoma present nutritional alterations and metabolic disorders that negatively impact the prognosis. Objective -The objective is to identify alterations in the metabolism of macro and micronutrients among liver cirrhosis patients with and without hepatocellular carcinoma and their relation to the Child-Turcote-Pugh score and Barcelona Clinic Liver Cancer staging. Methods -Analytical transversal study, with 31 hepatocellular carcinoma patients and 48 liver cirrhosis patients. Laboratorial exams were carried out. The existence of an association between the biochemical parameters and the disease severity as well as the presence of hepatocellular carcinoma was assessed. Results -The metabolic-nutritional profile of liver cirrhosis patients caused by the hepatitis C virus and hepatocellular carcinoma showed alterations, specifically the lipid (total cholesterol, HDL and triglycerides), protein (albumin, creatinine and uric acid), iron (transferrin, iron and ferritin saturation), hematocrit and hemoglobin, zinc and B12 vitamin profiles. There is a relation between nutritional biochemical markers and the Child-Turcote-Pugh, as well as Barcelona Clinic Liver Cancer staging. Conclusion -Considering the existence of alterations in the metabolism of nutrients in liver cirrhosis patients with and without hepatocellular carcinoma, and also that conventional nutritional assessment methods present limitations for this population, the biochemical laboratorial exams are valid to complement the diagnosis of the nutritional state in a quick and practical manner.
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