RESUMENSe presenta una revisión bibliográfica del mecanismo de infección y transformación neoplásica producida por el virus papiloma humano, de alto riesgo oncogénico, en el epitelio cervical. Se expone la interacción cápside receptor, internalización celular, expresión de genes tempranos, integración del genoma viral al de la célula huésped y algunos mecanismos vinculados a la proliferación y desarrollo neoplásico.
PALABRAS CLAVES: Virus papiloma humano, infección cervical, transformación neoplásica SUMMARYA bibliographical revision of the infection mechanism and neoplastic transformation produced by human papilloma virus of high risk in cervical epithelium is presented. The capside receptor interaction, internalization, early genes expression, integration of genoma to the host cell and mechanisms associated to the cell multiplication and neoplastic growth is described.
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