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Introduction:Sentinel lymph node biopsy (SLNB) was designed as a minimally invasive method for evaluation of nodal involvement in patients with penile cancer and nonpalpable lymph nodes. Nevertheless, SLNB is not used in a regular basis due to the lack of studies that adequately characterize the performance of this procedure. The purpose of this study was to evaluate the diagnostic performance of SLNB in patients with infiltrative penile carcinoma without palpable inguinal lymph nodes in a Colombian population.Materials and Methods:This is a retrospective observational study of 89 patients diagnosed with infiltrative penile squamous cell carcinoma with nonpalpable inguinal lymph nodes. These patients underwent partial or complete penectomy, along with SLNB, between 2008 and 2017. Those individuals with a positive SLNB underwent inguinal lymphadenectomy, while those with a negative SLNB were followed on a quarterly basis with a physical examination and imaging to assess relapse. Statistical analysis was done using the STATA 14 software. A contingency table was made to calculate sensitivity, specificity, positive predictive value, negative predictive value, and exactitude, each one with its own confidence interval (CI) of 95%.Results:There was an average follow-up of 31.4 months, and all 89 patients were evaluated; most primary tumors were T2 (55%), followed by T1 (37%), all of which were subclassified as T1b and T3 (8%). Tumours were most frequently located in the glans (43%). All patients were classified as cN0 and underwent SLNB. Sixty-one patients (69%) tested negative in the SLNB, four of whom (6%) presented with lymph node relapse. On the other hand, 28 patients (31%) tested positive in the SLNB and consequently underwent inguinal lymphadenectomy, seven of whom had negative lymph nodeinvolvement (25% false positives). According to the results, the sensitivity was 84% (95% CI, 65.3–93.6) and the specificity was 89% (95% CI, 79.4–94.7), with a false-negative rate of 6.5%.Conclusions:The SLNB using radiotracer can be a useful method for lymph node staging in patients with penile cancer and nonpalpable lymph nodes when performed in experienced centers.

Resumen Introducción El síndrome metabólico es una condición muy prevalente en nuestra sociedad, y durante las últimas dos décadas la prevalencia ha aumentado significativamente convirtiéndose en un problema con una carga en salud importante. El cáncer de próstata por su parte es la primera causa de cáncer en hombres en el mundo. Numerosos estudios han sugerido una asociación entre la presencia de síndrome metabólico y el diagnóstico de cáncer de próstata. La información acerca de la asociación Del cáncer de próstata y obesidad es controversial. Nuestro objetivo es determinar si existe una relación entre la presencia de obesidad y el diagnóstico de cáncer de próstata en adultos mayores de la ciudad de Bogotá. Objetivos y Métodos Se analizaron los datos del estudio Salud, Bienestar y Envejecimiento (SABE) Bogotá 2012. Se utilizó como variable dependiente el autorreporte de examen de próstata en los 2 últimos años y se evaluó con respecto a variables antropométricas así como factores sociodemográficos por medio de un análisis multivariado. Resultados La prevalencia de cáncer de próstata fue de 3,15%. El 31.9% de los hombres tienen un IMC mayor de 30. Se encontró una asociación significativa entre el IMC y el diagnóstico de cáncer de próstata (p = 0.005), Enfermedad coronaria y cáncer de próstata (p = 0.03) y nivel de escolaridad y diagnóstico de Cáncer de próstata (p = 0.012). Conclusión Nuestro estudio demuestra que existe una asociación significativa entre estas dos entidades en una población bogotana de adultos mayores. Es necesario realizar más estudios que aporten mayor información acerca de esta asociación.

Introducing the topic of abdominal wall metastasis secondary to prostate cancer with a reminder of the disease's rarity, being the first published case. This article is about a 66 year old patient diagnosed with prostate cancer [cT2aNxMx iPSA: 5,6 ng/ml Gleason 3+3, (Grade 1 Group)], treated with radical prostatectomy as well as accompanied with amplified pelvic lymphadenectomy, who subsequently presented metastatic lesions to the abdominal wall diagnosed with PET/CT Gallium 68-PMSA technique and treated with abdominal metastasectomy with adequate short term results.