No abstract

Exposure of DNA to oxidative stress produces strand scission and a variety of damaged nucleotides, which can be mutagenic and/or cytotoxic. The determination of the effects of specific lesions on nucleic acid structure, stability, and their interaction with polymerase and repair enzymes provide a chemical basis for the biological effects of DNA damage. [1,2]

No abstract

No abstract

Exposure of DNA to oxidative stress produces strand scission and a variety of damaged nucleotides, which can be mutagenic and/or cytotoxic. The determination of the effects of specific lesions on nucleic acid structure, stability, and their interaction with polymerase and repair enzymes provide a chemical basis for the biological effects of DNA damage. [1,2]