Gangliogliomas are central nervous system (CNS) tumors with a neuronal and glial component considered grade 1 according to the World Health Organization (WHO) classification. On the other hand, oligodendrogliomas are diffuse infiltrating gliomas (CNS WHO grade 2 or 3) characterized by both an isocitrate dehydrogenase mutation and 1p/19q co-deletion. There have been some cases with the coexistence of these two tumors. Here, we present the case of a low-growing left frontoparietal brain tumor with a definite diagnosis of ganglioglioma (CNS WHO grade 1) and oligodendroglioma (CNS WHO grade 2) with areas of anaplastic oligodendroglioma (CNS WHO grade 3) in a patient with long-standing epilepsy.
Dandy-Walker Malformation (DWM) and Pilocytic Astrocitoma are both rare disease entities that typically manifest early in life are associated with congenital etiological factors. DWM is a cerebellar malformation associated with a series of anatomical changes.The disease onset is usually at bith or during infancy. Late onset in adulthood is uncommon., Pilocytic astrocytoma is a tumor that arises from glial cells, primarily astrocytes, and is classified as grade I by the WHO. It is typically diagnosed in children and is frequently found in the posterior fossa. Concomitant occurrence of DWM and Pilocytic Astrocytoma there are very few reported cases.
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