No abstract

A unique brush coating technique was adopted to prepare high microwave absorbing super‐hydrophobic bactericidal fabrics. 3D micro‐CT, field emission scanning electron microscopy (FE‐SEM) and high resolution transmission electron microscopy (HR‐TEM) analyses were employed to establish the composite morphology. X‐ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) were used to characterize the embedded silver nanoparticles in the cotton fabrics. The developed thin wearable coated fabrics hold the lowest resistivity of 8 ohm‐cm−2 (lighten up series of LEDs) and electromagnetic interference (EMI) shielding effectiveness (SE) of 30.07 dB at 0.3 mm coating thickness within the X‐band frequency range. These thin coated fabrics can be the used in the flexible electronic devices along with extreme bactericidal feature against E. coli.

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Non–homologous end–joining DNA repair is essential for the survival and sustenance ofM·tuberculosis(Mtb) in the dormant stage of its life cycle. The ability of Mtb to sustain itself in the inactive form has been reported to be the critical factor for its resilience over the years. To unravel one of the salient features of the Mtb′s arsenal, we exploitedin silicoandin vitrotools to characterize the DNA binding properties of mycobacterial protein Ku (mKu) and its role in mycobacterial NHEJ. Here, we report the strong affinity of mKu for linear dsDNA exhibiting positive cooperativity for dsDNAs (40bp long or more). Molecular dynamics complemented within vitroexperiments showed that the DNA binding of mKu provides stability to both mKu homodimer and the DNA. Furthermore, mKu end capping of DNA was seen to protect the DNA termini against nucleolytic degradation by exonuclease. The DNA–mKu association formed higher–order oligomers probably due to the lodgement of two DNA molecules at opposite ends of the mKu homodimer. The ability of mKu to form continuous filament–like structures with DNA indicated its potential role in mycobacterial NHEJ synapsis.