Introduction: Parkinson's disease is a common progressive neurovegetative disorder, associated with rigidity, bradykinesia, tremor and postural instability; the conditions are not only limited to the extremities but can extend to the striated muscles within the upper airways and rib cage [1]. Anesthetic management in these patients can be difficult during the preoperative, intraoperative, and postoperative period. Objective: present the clinical case of an 81-year-old man diagnosed with Cholelithiasis, who underwent laparoscopic cholecystectomy at the Hospital General Enrique Garcés, who manifested an adverse event after extubation in the recovery room. Conclusion: upper airways present modifications in Parkinson's patients, this can difficult their management. The prevention of complications during this process will be largely due to the adequate pharmacological treatment for Parkinson's disease or its prompt introduction, and knowledge of the pharmacological effects of the different agents used during the anesthetic period.