We report our experience of allogeneic peripheral blood stem cell transplantation using non-myeloablative conditioning regimens delivered and supported on an outpatient basis. A group of 44 patients underwent 47 allograft procedures using peripheral blood stem cells. Approximately one third of the individuals did not require red blood cells transfusions: the median of transfused red blood cells units was 1 (range 0-10). In addition one out of three did not require platelet transfusions either, the median of platelet transfusions being 1 (range 0-6). In fourteen allografts (30%) neither red blood cells nor platelet transfusions were used. An inverse correlation was found between the number of CD34 cells infused and the PRBC and PLT transfusion requirements, those patients receiving high numbers of CD34 cells needing fewer transfusions of both PRBC and platelets. The possibility of conducting allografts without transfusion of blood products in some patients may result in a decrease in both cost and the risks stemming from exposure to human blood derivatives.

Esta investigación muestra cómo el alumnado percibe la actividad de la universidad en cuanto a la pertinencia de la formación que recibe. La pertinencia es analizada con base en tres dimensiones centrales de los aprendizajes que, se supone, los alumnos adquieren en su paso por el campus: aprendizajes para hacer, para convivir y para seguir aprendiendo a lo largo de la vida.La información analizada proviene de la encuesta “La reforma universitaria desde la perspectiva de los alumnos, UAMI 2014” que fuera realizada sobre una muestra de 283 estudiantes, representativa de la población estudiantil con actividad regular en la Universidad Autónoma Metropolitana, campus Iztapalapa (UAMI). Este campus se ubica en la zona oriente de la ciudad de México. El análisis de las percepciones estudiantiles, relacionadas con cada una de las dimensiones mencionadas, se basó en la construcción de tres índices sintéticos correspondientes.Los resultados indicaron que los estudiantes tienen la expectativa de que la formación recibida debería tener utilidad, sobre todo, para “aprender a hacer” y “aprender a aprender”, y no tanto para “aprender a convivir”. Sin embargo, la labor educativa concreta de la universidad, de acuerdo con la propia valoración estudiantil, guarda cierta relación con las expectativas de “aprender a hacer” y “aprender a convivir”, más no tanto con las de “aprender a aprender”.

The role of circumcision in partially protecting against sexually transmitted infections (STIs) and other dermatoses has been documented. Neonatal circumcision is not routinely practiced in South America. Although it is logical to assume that male genital dermatoses are more prevalent in Hispanic men, they are underrepresented in the existing literature. Objective: To describe the epidemiological characteristics from our male genital dermatology unit in Montevideo (Uruguay), the diagnoses, and correlate them with circumcision status and comorbidities. Methods: A retrospective observational cohort study was conducted. A dermatologist and urologist evaluated all patients using standard questionnaires. In 3 years and 8 months, 269 patients were seen. Median age was 41, prevalence of neonatal circumcision was 0.7%, HIV was 4.2%, STIs were 24.9%, non-STIs were 63.9%, and both (STI + non-STI) were 11.2%. Most frequent entities: eczema/balanoposthitis (27.1%), condyloma (24.9%), and lichen sclerosus (15.6%). Data correlating circumcision and other diagnoses did not reach statistical significance. HIV was positively associated with other STIs ( p < 0.05), and an association with balanoposthitis was seen; however, it did not reach statistical significance ( p < 0.1). Main limitation was small sample size. This is the first study of its kind based on Hispanic patients. Collaboration between specialties proved to be fundamental. Further studies are needed in this demographic to find an association between circumcision, comorbidities, and genital dermatoses.

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abajo firmantes, aprobaron la tesis titulada "Expresión de los genes Sbvp1 y SbGA20-oxidasa en las líneas de sorgo Redland B2 e IS9530" con fecha