Abstract. Contact dermatitis is inflammation of the skin caused by contact with exogenous substances characterized by itching, redness, scaling, vesicles and papules. Trigger factors for contact dermatitis can come from exposure to chemicals, personal hygiene, duration of contact, and other individual factors. The purpose of this study is to explain the risk factors for contact dermatitis in workers. The method used is a literature study by collecting several previous studies regarding risk factors for contact dermatitis in workers. The results of this study explain contact dermatitis starting from definition, causes, risk factors, pathogenesis, and signs and symptoms. Thus it can be concluded that the risk factors for contact dermatitis can come from exposure to chemicals for a long time, type of work, and other individual factors. Abstrak. Dermatitis kontak adalah inflamasi pada kulit yang disebabkan oleh kontak dengan zat eksogen yang ditandai dengan gatal, kemerahan, bersisik, vesikula, dan papul. Faktor pemicu dermatitis kontak dapat berasal dari paparan bahan kimia, personal hygiene, lama kontak, dan faktor individu lain. Tujuan penelitian ini adalah menjelaskan mengenai faktor risiko dermatitis kontak pada pekerja. Metode yang digunakan adalah studi literatur dengan mengumpulkan beberapa penelitian terdahulu mengenai faktor risiko dermatitis kontak pada pekerja. Hasil dari penelitian ini menjelaskan mengenai dermatitis kontak mulai dari definisi, penyebab, faktor risiko, patogenesis, dan tanda gejala. Dengan demikian dapat disimpulkan faktor risiko dermatitis kontak dapat berasal dari paparan bahan kimia dalam waktu lama, jenis pekerjaan, dan faktor individu lainnya.

Abstract. Tuberculosis (TB) is an infectious disease caused by infection with the bacterium Mycobacterium tuberculosis. In TB patients with Diabetes Mellitus (DM), chronic hyperglycemia impairs immunity and causes prolonged treatment. The aim of this study was to analyze the relationship between DM comorbidities and the success of pulmonary TB treatment. This cross-sectional study used secondary data from the TB information system (SITB) and medical records. The subjects of this study were pulmonary TB patients undergoing treatment at Al Ihsan Hospital during 2020. The inclusion criteria included a minimum age of 19 years, pulmonary TB, and completion of treatment. Research data included TB DM status and treatment outcomes. The end result of complete treatment includes cured and complete. Total TB patients were 1319 people with adult pulmonary TB as many as 634 people who met the inclusion criteria. Most of the pulmonary TB patients were male, 360 people (56.78%) and adults (20-59 years) 455 people (71.77%). Pulmonary TB patients with comorbid DM were 12 people (1.89%) and 622 people without DM (98.11%). There are 10 out of 12 TB DM patients who have incomplete treatment outcomes. There is no relationship between DM comorbidities and the success of pulmonary TB treatment with a P value of 2.517 (P value > 0.05). The conclusion of this study is that there is no relationship between DM comorbidities and treatment success rates. Abstrak. Tuberkulosis (TB) adalah penyakit menular akibat infeksi bakteri Mycobacterium tuberculosis. Pada penderita TB dengan Diabetes Melitus (DM), hiperglikemia kronis merusak imunitas dan menyebabkan lamanya pengobatan.Tujuan penelitian ini menganalisis hubungan komorbid DM dengan keberhasilan pengobatan TB Paru. Penelitian cross sectional ini menggunakan data sekunder sistem informasi TB (SITB) dan rekam medik. Subjek penelitian ini adalah pasien TB paru yang menjalani pengobatan di RSUD Al Ihsan selama tahun 2020. Kriteria inklusi meliputi usia minimal 19 tahun, TB paru, dan menyelesaikan pengobaan. Data penelitian meliputi status TB DM and hasil akhir pengobatan. Hasil akhir pengobatn lengkap meliputi sembuh dan lengkap. Total pasien TB sebanyak 1319 orang dengan TB paru dewasa sebanyak 634 orang yg memenuhi krikteria inklusi. Sebagian besar pasien TB paru memiliki jenis kelamin laki-laki 360 orang (56.78%) dan usia dewasa (20-59 tahun) 455 orang (71.77%). Pasien TB paru dengan komorbid DM 12 orang (1.89%) dan tidak DM 622 orang (98.11%). Terdapat 10 dari 12 orang pasien TB DM memiliki hasil akhir pengobatan tidak lengkap. Tidak terdapat hubungan antara komorbid DM dengan keberhasilan pengobatan TB paru dengan P value 2.517 (P value > 0.05). Simpulan dari penelitian ini adalah tidak terdapat hubungan komorbid DM dengan angka keberhasilan pengobatan.

Abstract. Stress is one of the physiological reactions in an individual where various defense mechanisms occur to face situations that are considered threatening or increased demands. One of the ways to reduce stress levels is to exercise. Exercise will stimulate the production of beta-endorphin hormones which will have the effect of restoring mood and lowering cortisol levels. This research aims to analyze the relationship between the type and frequency of sports and the stress level of Faculty of Medicine students in Bandung. The research method used is descriptive comparative with cross-sectional. The subjects of this research are 135 students of the Faculty of Medicine in the City of Bandung, with simple random sampling. The type and frequency of sports were taken using the Godin Leisure-Time Exercise questionnaire, while the stress level was assessed using the Perceived Stress Scale. Data were analyzed with Fisher's Exact Test with a confidence level of 95% (α=0,05). The results of the research on the relationship between the type of sport and the level of stress obtained p=0.024 and the relationship between the frequency of sport and the level of stress obtained p=0.004. The conclusion of this research is that there is a relationship between the type and frequency of sports and the level of stress. Abstrak. Stres merupakan salah satu reaksi fisiologis pada suatu individu di mana terjadi mekanisme pertahanan yang beragam untuk menghadapi situasi yang dianggap mengancam atau tuntutan yang meningkat. Salah satu cara untuk menurunkan tingkat stres adalah berolahraga. Olahraga akan merangsang pengeluaran hormon beta-endorfin yang akan memberikan efek memulihkan suasana hati dan menurunkan kadar kortisol. Penelitian ini bertujuan untuk menganalisis hubungan  jenis dan frekuensi olahraga dengan tingkat stres Mahasiswa Fakultas Kedokteran di Bandung. Metode penelitian yang digunakan adalah deskriptif comparative dengan cross-sectional. Subjek pada  penelitian ini adalah Mahasiswa Fakultas Kedokteran di Kota Bandung berjumlah 135 orang, dengan pengambilan sampel secara simple random sampling. Jenis dan frekuensi olahraga diambil menggunakan kuisioner Godin Leisure-Time Exercise  sedangkan  tingkat stres dinilai menggunakan Perceived Stres Scale. Data dianalisis dengan uji Fisher’s Exact Test dengan tingkat kepercayaan 95% (α=0,05). Hasil penelitian hubungan jenis olahraga dengan tingkat stres didapatkan p=0.024 dan hubungan frekuensi olahraga dengan tingkat stres didapatkan p=0.004. Simpulan pada penelitian ini terdapat hubungan jenis dan frekuensi olahraga dengan tingkat stres.

No abstract

Anti-inflammatory effect of ethanolic extractions of Pleurotus ostreatus would measure on body temperature and the C-Reactive protein (CRP) in rats induced by carrageenan. In this study, 30 rats were divided; group I (normal control) group II (negative control- caraggenan), group III (positive control- ibuprofen 400 mg / time), group IV and V (treatment I and II: ethanolic extract at 250 and 500 mg / kg BB). The Rats’ body temperature was measured at 0, 2, 4, 6 hours and at the 6th hour the qualitative and semiquantitative CRP was examined. The results showed that the temperature was reduced in the 1st to 6th hour, with different patterns. The Kruskal Wallis test shows significant P-values in the 2nd hour (0.02) and 6th (0.02). The qualitative CRP was analyzed using the Fisher Test and showed a significance at 1:2 dilutions (p=0), while the semiquantitative CRP is only at 1: 1 a dilution (p=0.0). The ethanol extraction of Pleurotus ostreatus at the dose of 250 mg and 500 mg / Kg BB showed a decrease in temperature and CRP, which was quite good when compared with ibuprofen. This result confirms about anti-inflammatory effect of the mushroom.