Foi realizado um estudo retrospectivo, baseado no banco de dados eletrônico de um hospital universitário, com objetivo de investigar a prevalência dos germes causadores e suas suscetibilidades aos antibióticos em adultos (idade >18 anos), com infecção do trato urinário atendidos ambulatorialmente. Foram identificados 957 exames de urocultura positiva no período entre janeiro de 2000 e dezembro de 2004. Escherichia coli, Proteus mirabillis e Klebsiella sp foram três principais bactérias causadoras. Sulfametoxazol-trimetropim apresentou a maior (46,9%) prevalência de resistência bacteriana seguida por cefalotina (46,7%), ácido nalidíxico (27,6%) e nitrofurantoína (22,3%). Durante o período estudado, o ácido nalidíxico apresentou um aumento anual de 5,9% na taxa de resistência bacteriana (p= 0,02). Ciprofloxacina mostrou também a tendência de aumento, com um crescimento anual de 3,3% (p= 0,07). Este estudo demonstrou que os antibióticos amplamente recomendados no tratamento empírico da infecção do trato urinário em adultos apresentaram altas taxas de resistência bacteriana na população estudada.

OBJECTIVES: To describe gastrointestinal symptoms and interstitial cells of Cajal (ICC) number in the proximal ganglionated bowel from patients who had surgery for Hirschsprungs disease (HD). METHODS: From 2001 to 2014, 48 children with HD had surgery in a medical school hospital. The files of 24 patients who continue to be followed at this hospital were revised and histological samples corresponding to the proximal ganglionated bowel were selected to ICC count by immunohistochemistry c-Kit. CICs were counted in 10 high-power fields (HPF) and classified into groups, according to Hagger et al. (2000)1: sparse: = 1cell/HPF, few: 2 to 3 cells/HPF, moderate: 4 to 8 cells/HPF and many >8 cells/HPF. RESULTS: Most patients declared symptoms in the postoperative period. The clinical complaints and respective frequencies were: constipation (50%), vomiting (37.5%), retentive fecal incontinence (29.1%), recurrent abdominal pain (25%), abdominal distension (25%), diarrhea (16.6%) and enterocolitis (4.1%). Among symptomatic children, 12 were in the group sparse, 3 in the group few and 4 in the group moderate. There was no difference in ICC count between symptomatic and asymptomatic patients, p=0,721. CONCLUSION: A low number of ICC was found in 80% of the proximal ganglionated intestine from HD patients; this finding was not associated with post-operative complaints and could not be valuable as a predictive indicator of poor post-surgical outcome.