OBJECTIVES: To describe gastrointestinal symptoms and interstitial cells of Cajal (ICC) number in the proximal ganglionated bowel from patients who had surgery for Hirschsprungs disease (HD). METHODS: From 2001 to 2014, 48 children with HD had surgery in a medical school hospital. The files of 24 patients who continue to be followed at this hospital were revised and histological samples corresponding to the proximal ganglionated bowel were selected to ICC count by immunohistochemistry c-Kit. CICs were counted in 10 high-power fields (HPF) and classified into groups, according to Hagger et al. (2000)1: sparse: = 1cell/HPF, few: 2 to 3 cells/HPF, moderate: 4 to 8 cells/HPF and many >8 cells/HPF. RESULTS: Most patients declared symptoms in the postoperative period. The clinical complaints and respective frequencies were: constipation (50%), vomiting (37.5%), retentive fecal incontinence (29.1%), recurrent abdominal pain (25%), abdominal distension (25%), diarrhea (16.6%) and enterocolitis (4.1%). Among symptomatic children, 12 were in the group sparse, 3 in the group few and 4 in the group moderate. There was no difference in ICC count between symptomatic and asymptomatic patients, p=0,721. CONCLUSION: A low number of ICC was found in 80% of the proximal ganglionated intestine from HD patients; this finding was not associated with post-operative complaints and could not be valuable as a predictive indicator of poor post-surgical outcome.
Behind the scenes of an anarchist newspaper: the particularities of the production process of a libertarian newspaper in the First Brazilian Republic (1900-1935) Lucas Thiago Rodarte Alvarenga * RESUMO: Como era produzido um jornal destinado à propaganda anarquista no início do século XX? Para dar conta dessa pergunta, o presente artigo vai em busca de fontes jornalísticas publicadas em São Paulo entre 1900 e 1935, com o objetivo de elencar as particularidades envolvidas no processo de feitura de um periódico libertário, no que tange os atores envolvidos, o processo de financiamento, a escolha da tipografia e impressão e sua distribuição. Para tal, foram escolhidos os jornais A Lanterna,
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