This study aims to determine the effect of methanol extract of mangrove leaves Rhizopora sp. on increasing the number of erythrocytes in anemic rats in vivo. This type of research is a laboratory experimental research. The research design used was a post only control group design using a sample of 4 treatments and each treatment with 5 replications. The sample in this study was a sample taken, namely mice aged 3-4 months with a body weight of 20-25 grams. Male mice (Musmusculus L) and mangrove Rhizophora sp. taken from the coastal village of Lembar. This study used two treatments, namely P1 (methanol extract of mangrove leaves 100mg/kgbb and P2 (methanol extract of mangrove leaves 200mg/kgbb), while for positive control (Ferro Fumarate), and negative control (aquadest). sp. to the increase in the number of anemic mice in vivo K-, K+, PI, and P2, respectively, the average number of erythrocytes was 3.55 x 106/mm3, 7.01 x 106 / mm3, 7.848 x 106 / mm3 and 9.056 x 106 / mm 3. The data were obtained using the ANOVA statistical test to determine whether there was a difference in the effective dose of each treatment, it was necessary to continue with the LSD test, the results were not significantly different between K+, P1 and P2 but significantly different from K- which means there was an effect of giving extract Mangrove leaf methanol on increasing the number of erythrocyte anemia in vivo.
Demam tifoid merupakan penyakit yang disebabkan oleh infeksi bakteri Salmonella typhi yang merupakan penyakit endemik yang dapat menyerang banyak orang dan masih menjadi masalah kesehatan di daerah tropis terutama di negara-negara berkembang termasuk Indonesia. Berbagai upaya pencegahan, pengobatan dan terapi yang telah dilakukan untuk mengurangi permasalahan infeksi bakteri. Alternatif baru yang terus diteliti dan dikembangkan adalah pengobatan menggunakan tanaman herbal. Salah satu tanaman yang dapat dimanfaatkan sebagai alternatif dalam pengobatan infeksi bakteri adalah tumbuhan pinang (Areca catechu L.) yang memiliki kandungan senyawa sebagai antibakteri seperti alkaloid, flavonoid dan tanin. Tujuan penelitian ini adalah untuk mengetahui aktivitas antibakteri ekstrak biji buah pinang (Areca catechu L.) dalam menghambat pertumbuhan Salmonella typhi, untuk menentukan Konsentrasi Hambat Minimum (KHM) dan Konsentrasi Bunuh Minimum (KBM) ekstrak biji buah pinang (Areca catechu L.) dalam menghambat pertumbuhan Salmonella typhi. Metode yang digunakan dalam penelitian ini adalah dilusi cair yang digambarkan sebagai efek bakteriostatik dan dilusi padat yang digambarkan sebagai efek bakterisidal. Jenis penelitian ini adalah eksperimental laboratories dengan desain the post only control group desain dengan menggunakan analisa data uji statistik versi 16. Hasil penelitian ini adalah ekstrak biji buah pinang (Areca catechu L.) mampu menghambat pertumbuhan Salmonella typhi. Konsentrasi Hambat Minimum (KHM) ekstrak biji buah pinang (Areca catechu L.) didapatkan pada konsentrasi 1%. Konsentrasi Bunuh Minimum (KBM) ekstrak biji buah pinang (Areca catechu L.) tidak didapatkan karena pada semua media Nutrient agar terdapat pertumbuhan bakteri. Adanya pertumbuhan bakteri tersebut memberikan makna bahwa ekstrak biji buah pinang (Areca catechu L.) hanya mampu menghambat (bakteriostatik) namun tidak mampu membunuh
Tuberculosis is a disease caused by rod-shaped bacteria (basil) with another name Mycrobacterium tuberculosis. Mycrobacterium tuberculosis enters the body then causes inflammation, inflammation and bacterial invasion which then induces liver cells to synthesize acute phase C-reactive protein protein (CRP). CRP will increase sharply after inflammation, as well as the formation of aggregates derived from the acute phase protein hormone which causes an increase in the Erythrocyte sedimentation rate (ESR)). The purpose of this study was to determine the relationship Erytrocyte sedimentation rate (ESR) and levels of C-Reactiv protein (CRP) in tuberculosis (TBC) patients. This research is an analytical descriptive study using cross sectional. Data collectors are done using the Non Random Accidental Sampling technique. The number of respondents in this study were 11 people with tuberculosis. Based on the results of this study it is known that TBC patients with smear negative as much as 7 people (63.6%) and TB patients with positive smear as much as 4 people (36.4%), both in TB patients with negative smear and positive smear both have levels of ESR not normal with an average ESR level in positive smear of 101.3 mm / hour and the average ESR level in smear negative is 20.8 mm / hour. All TBC patients with smear positive CRP levels (not normal) with an average mean value of CRP of 36 mg / L or an average CRP level in TBC smear negative patients of 0.9 mg / L. Based on the Pearson test results between levels of erythrocyte sedimentation rate (ESR) with C-Reactive protein (CRP) in tuberculosis (TBC) patients obtained a value of p <0.01 (0.000 <0.01). This shows a strong relationship between LED and CRP levels in TB patients
Typhoid fever is one of the diseases that attack the human digestive tract that has a close relationship with environmental sanitation factors. Typhoid fever is transmitted through food and drink contaminated by Salmonella typhi and is an infectious disease. This type of research is descriptive analytics that aims to look for relationships between variables. The method used in the Widal test is agglutination while on Anti Salmonella typhi IgM examination is Inhibition Magnetic Binding Immunoassay (IMBI). The object of the study was a patient indicated by typhoid fever who examined Widal test and Anti Salmonella typhi IgM in the laboratory of Prodia Mataram Clinic, included in the inclusion criteria of 57 people. Based on the results of the study, widal test examination with fever day 3 to day 7 obtained the number of widal test positive patients 4 people (7%) while in Anti Salmonella typhi IgM obtained positive results 14 people (24.6%). At the Widal test with fever day 3, 2 people were positively infected with Salmonella typhi with titers 1/320 while on the 6th and 7th day fever each one person was positive with titers 1/320 and 1/640. At the Anti Salmonella typhi IgM examination on fever days 3 to 5 there were 4 people positively infected with Salmonella typhi scale 4 to 6, while on the 6th and 7th days were obtained.
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