Considering a variety of sampled value (SV) attacks on busbar differential protection (BDP) which poses challenges to conventional learning algorithms, an algorithm to detect SV attacks based on the immune system of negative selection is developed in this paper. The healthy SV data of BDP are defined as self-data composed of spheres of the same size, whereas the SV attack data, i.e., the nonself data, are preserved in the nonself space covered by spherical detectors of different sizes. To avoid the confusion between busbar faults and SV attacks, a self-shape optimization algorithm is introduced, and the improved self-data are verified through a power-frequency fault-component-based differential protection criterion to avoid false negatives. Based on the difficulty of boundary coverage in traditional negative selection algorithms, a self-data-driven detector generation algorithm is proposed to enhance the detector coverage. A testbed of differential protection for a 110 kV double busbar system is then established. Typical SV attacks of BDP such as amplitude and current phase tampering, fault replays, and the disconnection of the secondary circuits of current transformers are considered, and the delays of differential relay operation caused by detection algorithms are investigated.
Aims:Our team tested spinal cord fusion (SCF) using the neuroprotective agent polyethylene glycol (PEG) in different animal (mice, rats, and beagles) models with complete spinal cord transection. To further explore the application of SCF for the treatment of paraplegic patients, we developed a new clinical procedure for SCF called vascular pedicle hemisected spinal cord transplantation (vSCT) and tested this procedure in eight paraplegic participants.Methods: Eight paraplegic participants (American Spinal Injury Association, ASIA: A) were enrolled and treated with vSCT (PEG was applied to the sites of spinal cord transplantation). Pre-and postoperative pain intensities, neurologic assessments, electrophysiologic monitoring, and neuroimaging examinations were recorded.Results: Of the eight paraplegic participants who completed vSCT, objective improvements occurred in motor function for one participant, in electrophysiologic motor-evoked potentials for another participant, in re-establishment of white matter continuity in three participants, in autonomic nerve function in seven participants, and in symptoms of cord central pain for seven participants.
Conclusions:The postoperative recovery of paraplegic participants demonstrated the clinical feasibility and efficacy of vSCT in re-establishing the continuity of spinal nerve
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.