Background: Endoscopic transforaminal decompression and interbody fusion (ETDIF) has been widely discussed due to its advantages of less trauma, less bleeding, quick recovery, high safety, and relatively fewer complications, as well as adverse factors such as incomplete decompression, steep learning curve, low fusion rate, and high radiation risk. Furthermore, this technique requires the use of supplemental posterior pediclescrew. Decompression, interbody fusion and percutaneous pedicle screw implantation are not completed in a single channel. Percutaneous endoscopic transforaminal oblique fixation from posterior corner in lumbar spine (PETOFPC) overcomes the above limitations. The purpose of this study is to confirm the anatomical feasibility for PETOFPC in the posterolateral transforaminal approach and to provide anatomic data for the design of new integrated fixable and fused interbody cage.Methods: Sixty volunteers (22 men and 38 women) who underwent lumbar CT scans were collected and sent to the GEAW4.4 workstation. As a cohort study, the distances and angles of each path in the sagittal and axial planes were measured and analyzed statistically.Results: The lengths of each path are not less than 40mm, and the longest can be up to 46mm. The paths in full-length group are about 5mm longer than that in medium group. PE (from point P to target E) path was the optimal path. The angles of each path were significantly different (P≤0.001), namely, a1 > a2 > a3, b1 > b2 > b3, and c1 < c2 < c3.Conclusions: This study confirms anatomic feasibility for PETOFPC and provides anatomic data for the design of new integrated fixable and fused interbody cage. PETOFPC may be a very promising technology and have great clinical significance.

Background: Traditional lumbar interbody fusion has many limitations, such as large trauma, severe damage to the normal posterior structure, and long postoperative recovery period. With the advance of minimally invasive surgery and spinal endoscopy, new fusion technologies such as percutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) and endoscopic transforaminal lumbar interbody fusion (Endo-LIF) through Kambin’s triangle with less trauma, less bleeding and faster recovery have been developed. However, nerve root injury and dural tears are important complications, and Kambin’s triangle is not "safe". Moreover, fusion after decompression often requires placement of a 14-mm channel, removal of more articular processes, fixation with posterior percutaneous pedicle screw, and changes of intraoperative position or anesthesia, which are inconvenient. One-stop percutaneous endoscopic transforaminal oblique fixation from posterior corner in lumbar spine overcomes the above limitations, and realizes one-stop decompression, fusion and fixation in a single regular minimally invasive channel. The purpose of this study is to measure the neuroimaging anatomic parameters of the nerves related to oblique fixation from posterior corner in lumbar spine through Kambin’s triangle, to define and evaluate the safe working area in Kambin’s triangle, and to identify the optimal target area for endoscopic fusion and fixation.Methods: Sixty volunteers (27 males and 33 females) underwent lumbar MR examination (VISTA,3D-STIR-TSE Sequence) and the data were uploaded to Philips (Achieva 1.5T MR) workstation. Three working targets (P1, P2, P3) were preset for oblique fixation from posterior corner in lumbar spine. The distances from the working targets to exiting nerve roots and dural sac/traversing nerve roots in the coronal and sagittal planes, and the distances from the exiting roots to the dural sac/traversing nerve roots in the upper and lower endplate planes were measured and statistically analyzed.Results: In L1/2–L5/S1, the P values of paired t-test for the distances (c1, c2, c3, c4, c5 and c6) from each target (P1, P2 and P3) to the ipsilateral exiting nerve roots and dural sac/traversing nerve roots were all greater than 0.05. There were no statistically significant differences between the targets at both sides of the same segment, and the mean values of both sides were calculated. The c1, c2, c3, c4, c5 and c6 all increased and then decreased, gradually increased from L1/2, maximized in L4/5, and decreased slightly in L5/S1. As the targets (P1, P2, P3) moved laterally along the horizontal midline of the posterior margin of intervertebral disc, the distance to the dural sac/traversing nerve roots gradually increased, while the distance to the exiting roots gradually decreased. The distance from P1 to exiting nerve roots was significantly greater (1–3 mm) than that to dural sac/traversing nerve roots. The distance from P3 to exiting nerve roots was significantly smaller (1–3 mm) than that to dural sac/traversing nerve roots. The distances from P2 to exiting nerve roots and to dural sac/traversing nerve roots did not different significantly in each segment, and the differences in means were within 1 mm.The distances from exiting nerve roots to dural sac/traversing nerve roots in the upper and lower endplate planes (d1, d2) gradually increased in L1/2–L5/S1 (P<0.0001) and the means of d2 were greater than d1 (P<0.05). There was no statistically significant difference between the left and right sides in the upper and lower endplates in each segment (P=0.26).In L1/2–L5/S1, the P values of paired t-test for the distances (s1, s2, s3, s4, s5, s6) from the projection points of posterior-inferior (posterior-superior) corner of upper (lower) vertebral body to exiting nerve roots in the sagittal planes passing the targets were all greater than 0.05. There was no statistically significant difference between both sides of the same segment, and thus the mean value was calculated. With the outward shift of the targets in the sagittal planes, s1, s3 and s5 gradually decreased (s1>s3>s5), and the same trend was found for s2, s4 and s6 (s2>s4>s6). The distances gradually increased in each segment from the smallest value in L1/2 to the largest value in L5/S1.Conclusion: Kambin’s triangle can be used as a working area for oblique fixation from posterior corner in lumbar spine, but the actual safe area is smaller than theoretical prediction. The intersection point between the vertical line from the medial 1/3 of pedicle and the horizontal midline of the posterior margin of intervertebral disc (P2) is an ideal "target" for oblique fixation from posterior corner in lumbar spine. It is neuroanatomically feasible to achieve one-stop complete decompression, fusion, and fixation in a single channel under spinal endoscopy. Further biomechanical studies and clinical trials are needed to determine whether it can be a new option for posterior spinal fusion.

BackgroundPercutaneous endoscopic transforaminal lumbar interbody fusion (PE-TLIF) has been widely discussed due to its advantages of less trauma, less bleeding, quick recovery, high safety, and relatively fewer complications, as well as other adverse factors such as incomplete decompression, steep learning curve, low fusion rate, and high radiation risk. It can keep the posterior structure of spine intact to the greatest extent, ensure the stability of spine after surgery, and achieve decompression with minor trauma. However, posterior percutaneous pedicle screws are often needed for fusion and fixation after decompression, and additional posterior trauma, postural changes and anesthesia methods are often required. Interbody fixation and fusion are often independent and not one-stop completion. The authors consider whether the percutaneous spinal endoscopy can be used to achieve complete decompression and fusion under a single minimally invasive channel, while achieving one-stop endoscopic decompression, fusion and fixation. The purpose of this paper is to provide the anatomic feasibility for oblique fixation by measuring the imaging anatomic parameters, especially to provide the anatomic basis for the design of new endoscopic lumbar interbody fusion cage.Methods Sixty volunteers (22 men and 38 women) who underwent lumbar CT scans were collected and sent to the GEAW4.4 workstation. The distances from posterior corner in the lumbar spine to the corresponding targets of the contralateral anterior corner and the included angles between each path line in sagittal and axial plane were measured and analyzed statistically.Results In the medium group, PC path was the shortest, PA path and PB path had little difference (P=0.123), with no statistical significance. In the full-length group, PF path was the shortest, and there was no significant difference between PD path and PE path (P =0.177). PE was the optimal path. The included angles a1, a2, a3, b1, b2, and b3 in sagittal plane and c1, c2 and c3 in axial plane were significantly different (P=0.000), namely, a1 >a2>a3, b1>b2>b3, and c1<c2<c3. Conclusions This study provides anatomic feasibility for percutaneous endoscopic transforaminal oblique fixation from posterior corner in lumbar spine and particularly provides anatomic basis for the design of new endoscopic lumbar interbody fusion cage.