ABSTRACT. Concentrations of interferon-γ (IFN-γ) and tumor necrosis factor-α (TNF-α) were determined in serum and whey samples from cattle with naturally occurring coliform mastitis for two weeks after onset using bovine INF-γ-and TNF-α-specific ELISA. In serum and whey samples from healthy cows, IFN-γ was almost undetectable and TNF-α was detected at low levels. At the onset of illness, INF-γ in sera and whey and TNF-α in whey from the mastitic cows were significantly higher than their respective values in healthy cows. Concentrations of IFN-γ and TNF-α in whey from mastitic cattle decreased significantly as the cows recovered. KEY WORDS: bovine mastitis, interferon-γ, tumor necrosis factor-α.

Angew. C'hem. 1111. Ed. Engl. 29 (1990) No. 6 0 VCH Verlag.sgesell.schafi mbH, 0-6940 Weinheim, 1990 0570-0833/90j0606-0643 S 03.50+ .25/0 Angew. Chem. Inl. Ed. Engl. 29 (1990) No. 6 Q VCH Verlugsgesell.~chuji mbH. 0-6940 Weinheim, 1990 0570-0833~9~~0606-ocs4s S 03.50i .2S!O

Ein sehr niedriges erstes Oxidationspotential (0.15 V vs. SCE) charakterisiert die 12π‐Elektronen‐Titelverbindung 1, die durch Reduktion des entsprechenden 14π‐Elektronensystems mit Kalium und Abfangen des Dianions mit Methyliodid entsteht. Mit dem Elektronenacceptor 2 bildet 1 leitfähige Charge‐Transfer‐Komplexe (σ = 5.6 x 10−2 S cm−1).

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