Background
With an increasing incidence of obesity, the relationship between obesity and body image has become a hot research topic worldwide. From high school to university, young people experience changes in their social environment. University students have a high incidence of eating disorders and insufficient physical activity. The purpose of this study was to explore the relationship between body dissatisfaction, insufficient physical activity, and disordered eating behaviors among university students in southern China.
Methods
In total, 1296 university students aged 18–23 years were recruited for this study. The participants completed anthropometric measurements, the Physical Activity Rating scale-3 (PARS-3), and the Chinese-Dutch Eating Behavior Questionnaire (C-DEBQ). The ideal weight and silhouette were reported by university students using a questionnaire.
Results
Compared with men, young women had a higher level of body dissatisfaction. For men, body mass index (BMI; β = 0.76, P < 0.01), physical activity score (β = − 0.11, P < 0.01), and restrained eating score (β = 0.10, P < 0.01) were the significant factors predictive of body dissatisfaction. For women, BMI (β = 0.57, P < 0.01), muscle mass (β = 0.12, P < 0.01), physical activity score (β = − 0.11, P < 0.01), and restrained eating score (β = 0.09, P < 0.01) were the significant factors predictive of body dissatisfaction.
Conclusions
University students with high body dissatisfaction had lower physical activity scores and higher restrained eating scores. The data presented here highlight the impact of university students’ body dissatisfaction on physical activity deficiency and disordered eating behaviors in China.
BackgroundAutism spectrum disorders (ASD) are hereditary, heterogeneous and biologically complex neurodevelopmental disorders. Individual studies on gene expression in ASD cannot provide clear consensus conclusions. Therefore, a systematic review to synthesize the current findings from brain tissues and a search tool to share the meta-analysis results are urgently needed.MethodsHere, we conducted a meta-analysis of brain gene expression profiles in the current reported human ASD expression datasets (with 84 frozen male cortex samples, 17 female cortex samples, 32 cerebellum samples and 4 formalin fixed samples) and knock-out mouse ASD model expression datasets (with 80 collective brain samples). Then, we applied R language software and developed an interactive shared and updated database (dbMDEGA) displaying the results of meta-analysis of data from ASD studies regarding differentially expressed genes (DEGs) in the brain.ResultsThis database, dbMDEGA (https://dbmdega.shinyapps.io/dbMDEGA/), is a publicly available web-portal for manual annotation and visualization of DEGs in the brain from data from ASD studies. This database uniquely presents meta-analysis values and homologous forest plots of DEGs in brain tissues. Gene entries are annotated with meta-values, statistical values and forest plots of DEGs in brain samples. This database aims to provide searchable meta-analysis results based on the current reported brain gene expression datasets of ASD to help detect candidate genes underlying this disorder.ConclusionThis new analytical tool may provide valuable assistance in the discovery of DEGs and the elucidation of the molecular pathogenicity of ASD. This database model may be replicated to study other disorders.Electronic supplementary materialThe online version of this article (10.1186/s12859-017-1915-2) contains supplementary material, which is available to authorized users.
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