Aim. To develop an algorithm for a comprehensive assessment of endogenous and exogenous factors and risks of urinary tract infections (UTI) to improve prevention measures in multidisciplinary healthcare organizations.Materials and methods. All patients included in the study were divided into two groups. Group 1 was formed on the basis of the Altai Regional Hospital for War Veterans (700 medical histories). Regional Clinical Hospital provided 500 medical histories. Endogenous and exogenous risk factors were assessed in patients included in the study.Results. Following a comprehensive assessment of exogenous and endogenous risk factors of healthcare-associated UTI among patients of different ages, an algorithm for improving prevention measures has been developed.Conclusions. The algorithm of prevention measures for expert evaluation of risk factors and groups of healthcare-associated UTI enables the prevention of these infections to be improved. The creation of databases of risk factors that contribute to infection is essential for providing expert evaluation of standard operating procedures and internal quality audits of medical activities, as well as for determining the optimal prevention measures reducing the incidence of UTIs.

Urinary tract infections (UTIS) in the Russian Federation are widespread and often occur in children, adults, most often affecting people in the most active period of their lives. The course of UTI is determined by a number of predisposing factors, such as age, sex, General condition of the patient, the presence of immunocompromising factors. Uncontrolled use of antibacterial therapy is often a predisposing factor in the chronization of the process in the upper urinary tract.To determine the identity of E. coli strains. In 2019, biological material was collected from 50 patients of «Altai regional hospital for war veterans» with urinary tract infections (chronic pyelonephritis and chronic cystitis) to assess bacteriuria. According to the results of bacteriological research, 23 strains of E. coli were isolated. After that, molecular genetic analysis was performed using the Random Amplified Polymorphic DNA method of E. Coli strains obtained from patients with urinary tract infections, and their identity was evaluated. The results of this study showed that the method used is a reliable method of epidemiological mapping and determination of relationships between closely related varieties and strains of microorganisms isolated from various sources. Carrying out one bacteriological examination of urine in urinary tract infections is not enough, only high-tech techniques allow establishing the exact type of the causative agent of these infections and will allow selecting the correct appointment of antimicrobial drugs in patients with this group of infections.

In order to evaluate invasive interventions for the prognosis of development with urinary tract infections (UTIs), as a form of infections associated with the provision of medical care (ISMP)), 1200 patient case histories were selected among patients of different age groups for the period from 2007–2019. The patients were divided into 2 groups: group 1–700 patients (patients older than 65 years), group 2–500 patients (patients aged 18–64 years). Using the method of discriminant analysis (using the statistical computer package IBM SPSS 23), a prognostic function was constructed for patients of both age groups, when calculating which the indicators of surgical intervention in the kidney and bladder area and catheterization of the bladder were analyzed, as well as the combination of these indicators with the most common somatic diseases that were isolated among patients from both groups.

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