У статті використана авторська інноваційна математична дослідницька модель центральної прямотечійної системи кондиціювання повітря чистого приміщення. Мета моделі-комп'ютерне оцінювання ексергетичної ефективності вибраної системи кондиціювання та втрат ексергії в її елементах залежно від різних факторів, що впливають на її роботу. Завдяки цій моделі отримано діаграму Грассмана потоків та втрат ексергії для вибраної системи кондиціювання за температури зовнішнього повітря 42°С. Ключові слова: Ексергетичний баланс-Cистеми кондиціювання повітря-Чисті приміщення-Ексергетична ефективність-Діаграма Грассмана В.И. Лабай, Д.И. Гарасым Национальный университет «Львовская политехника», ул. Ст. Бандеры, 12, Львов, 79013 ДИАГРАММА ГРАССМАНА В ЕКСЕРГЕТИЧЕСКОМ АНАЛИЗЕ СИСТЕМ КОНДИЦИОНИРОВАНИЯ ВОЗДУХА ЧИСТЫХ ПОМЕЩЕНИЙ В статье использована авторская инновационная математическая исследователь-ская модель центральной прямоточной системы кондиционирования воздуха чис-того помещения. Цель модели компьютерная оценка эксергетической эффектив-ности избранной системы кондиционирования и потерь эксергии в ее элементах в зависимости от разных факторов, какие влияют на ее работу. Благодаря этой модели получено диаграмму Грассмана потоков и потерь эксергии для избранной системы кондиционирования при температуре наружного воздуха 42°С. Ключевые слова: Эксергетический баланс Системы кондиционирования воздуха Чистые помещения Эксергетическая эффективность-Диаграмма Грассмана This work is licensed under the Creative Commons Attribution International License (CC BY). http://creativecommons.org/licenses/by/4.0/ Холодильна техніка та технологія, № 5 (151), 2014 ____________________________________________________________________________________________________ 18 © В.Й. Лабай, Д.І. Гарасим, 2014 Перед складанням ексергетичних балансів по-трібно виділити ЕТС, яка підлягає дослідженню, для чого уявно відділяють її від інших об'єктів контрольною поверхнею, а ексергії всіх потоків речовини та ексергії, що проходять через неї вклю-чають в ексергетичний баланс. Ексергетичний баланс для даної ЕТС, тобто системи кондиціювання повітря чистого примі-щення, має такий вигляд: Холодильна техніка та технологія, № 5 (151), 2014 In modern technologies, which are related to energy transformation, namely in the air conditioning systems, important place are occupied by objects creation and improvement of which requires the use of innovation thermodynamics. Classic apparatus of this science is often insufficient to solve new tasks; it is necessary not only to its further development, but its combination with the elements of a systematic approach and energetic. Innovation mathematical research model of the central straight flow air conditioning system for cleanroom in order to computer's estimation its energy effective by virtue of exergetic output-input ratio and losses of exergy depending on different factors, which have influence on its work, was used in this article. The diagram of Grassmann of exergy flows and losses for chosen air conditioning system a...
The therapeutic effect of melatonin (MEL) against aluminum (Al)-induced neurotoxicity was investigated in mouse cerebellum. Two groups of male albino mice were intraperitoneally injected with Al acetate or MEL alone, at doses of 3.5 or 7 mg kg À1 day À1 , respectively, for 6 weeks. During this period, another group of animals received a combination of both Al and MEL (3.5 þ 7 mg kg À1 day À1 ). At the end of the treatment cerebellum was removed and processed to examine the oxidative stress markers: superoxide dismutase (SOD), catalase (CAT), and thiobarbituric acid-reactive substances (TBA-RS). Oxidative stress increased significantly with administration of Al which was estimated by increased TBA-RS and reduction in the activities of SOD and CAT. However, these alterations were significantly reversed significantly following MEL treatment which was observed in co-administered group. Protective effects of MEL were also observed at electron microscopic level. Ultrastructural studies revealed an increase in vacuolization, chromatin condensation within the nucleus, degenerated purkinje cell, degenerated axon and degenerated granule cells in the cerebellum of Al-treated mice group whereas concurrent administration of MEL with Al reduced these changes. The results of the present investigation emphasize the potential use of MEL as a supplement in therapy of free radical based neurological disorders in which oxidative stress is involved.
Lead is important heavy metal and due to widespread use in industry, it has become an important pollutant that exerts toxic effects on human health. Lifestyle factors (e.g. cigarette smoking), proximity to industrial areas, lead mines, lead based paints and leaded gasoline significantly contribute to lead pollution of the air, food, water and soil. Several antioxidant enzymes and molecules have been used to evaluate lead-induced oxidative damage. Present study aimed to evaluate the lead acetate induced cardio-toxicity. Lead acetate is known to induce changes in free radical scavenging enzymes like superoxide dismutase (SOD) and catalase (CAT). Healthy looking mice showing no sign of morbidity were divided into three groups. Group I was designated as control whereas group II and group III received lead acetate having doses 10 mg/kg body weight of lead acetate, daily and 150 mg/kg body weight of lead acetate, weekly respectively. Study was performed after 24 hours, 40 and 80 days stages. Lead acetate significantly decrease antioxidant enzymes and increase oxidative stress along with cardiac tissue damage.
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