Key indicatorsSingle-crystal X-ray study T = 120 K Mean (C-C) = 0.005 Å R factor = 0.052 wR factor = 0.127 Data-to-parameter ratio = 9.2 For details of how these key indicators were automatically derived from the article, see
The synthesis of some new 2-(6-methoxy-2-naphthyl)-5-aryl-1,3,4-oxadiazoles (4a-k) has been described. Ethyl-6-methoxy-2-naphthoate (1) yielded on treatment with hydrazine hydrate to 6-methoxy-2-naphthoic acid hydrazide (2). Compound 2 reacted with substituted aromatic carboxylic acids (3a-k) in phosphorus oxychloride yielded 2-(6-methoxy-2-naphthyl)-5-aryl-1,3,4-oxadiazoles (4a-k). Newly synthesized compounds were characterized by IR, (1)H-NMR and mass spectral data. All the compounds were screened for their anti-inflammatory and analgesic activity. Compound 4j exhibited promising anti-inflammatory and analgesic activities.
Key indicatorsSingle-crystal X-ray study T = 298 K Mean (C-C) = 0.007 Å R factor = 0.079 wR factor = 0.245 Data-to-parameter ratio = 22.4For details of how these key indicators were automatically derived from the article, see
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